Intra-Host Evolution of Norovirus GII.4 in a Chronic Infected Patient With Hematopoietic Stem Cell Transplantation

Intra-Host Evolution of Norovirus GII.4 in a Chronic Infected Patient With Hematopoietic Stem Cell Transplantation

Human noroviruses (NVs) are the leading cause of acute gastroenteritis outbreaks worldwide. The majority of outbreaks are caused by genogroup II.4 (GII.4), with new variants emerging every 2 to 4 years. Immunocompromised patients are hypothesized to be important reservoirs where new NV variants emer...

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Bibliographic Details
Main Authors: Jie-mei Yu, Ze-yin Liang, Ke Guo, Xiao-man Sun, Qing Zhang, Yu-jun Dong, Zhao-jun Duan
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-03-01
Series:Frontiers in Microbiology
Subjects:
human norovirus
evolution
chronic infection
intra-host
hematopoietic stem cell transplantation
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2020.00375/full

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