Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect

Androgens improve ovarian follicle function impaired by glucocorticoids through an androgen-IGF1-FSH synergistic effect

High concentrations of glucocorticoids caused by chronic stress are known to affect ovarian function and cause diminished ovarian reserve. Androgens are essential for early-stage ovarian follicle development, but the effects and mechanisms of androgens on follicle development under chronic stress re...

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Bibliographic Details
Main Authors: Lingyun Gao, Hongna Gao, Wenjun Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
glucocorticoids
androgen
IGF1
FSH
ovarian follicle
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.951928/full

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