Metabolic engineering of Zymomonas mobilis for co-production of D-lactic acid and ethanol using waste feedstocks of molasses and corncob residue hydrolysate

Metabolic engineering of Zymomonas mobilis for co-production of D-lactic acid and ethanol using waste feedstocks of molasses and corncob residue hydrolysate

Lactate is the precursor for polylactide. In this study, a lactate producer of Z. mobilis was constructed by replacing ZMO0038 with LmldhA gene driven by a strong promoter PadhB, replacing ZMO1650 with native pdc gene driven by Ptet, and replacing native pdc with another copy of LmldhA driven by Pad...

Full description

Bibliographic Details
Main Authors: Mimi Hu, Weiwei Bao, Qiqun Peng, Wei Hu, Xinyu Yang, Yan Xiang, Xiongying Yan, Mian Li, Ping Xu, Qiaoning He, Shihui Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
Zymomonas mobilis
native CRISPR-Cas system
lactate
beet molasses
corncob residue hydrolysate
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2023.1135484/full

Similar Items

Similar Items