Photoactivated adenylyl cyclases attenuate sepsis-induced cardiomyopathy by suppressing macrophage-mediated inflammation

Photoactivated adenylyl cyclases attenuate sepsis-induced cardiomyopathy by suppressing macrophage-mediated inflammation

Sepsis-induced myocardiopathy, characterized by innate immune cells infiltration and proinflammatory cytokines release, may lead to perfusion failure or even life-threatening cardiogenic shock. Macrophages-mediated inflammation has been shown to contribute to sepsis-induced myocardiopathy. In the cu...

Full description

Bibliographic Details
Main Authors: Guofang Xia, Hongyu Shi, Yuanyuan Su, Beibei Han, Chengxing Shen, Shiqiang Gao, Zhong Chen, Congfeng Xu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Immunology
Subjects:
macrophage
photoactivated adenylyl cyclase
inflammation
optogenetics
sepsis-induced myocardiopathy
cell-based therapy
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2022.1008702/full

Similar Items

Similar Items