Reduced CSF orexin levels in rats and patients with systemic inflammation: a preliminary study

Reduced CSF orexin levels in rats and patients with systemic inflammation: a preliminary study

Abstract Objective Sepsis is a lethal condition characterized by systemic inflammation and multiple organ failure; this condition was initially defined as systemic inflammatory response syndrome (SIRS) due to infection. We previously reported that the hypothalamic neuropeptide orexin improved surviv...

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Bibliographic Details
Main Authors: Yasuhiro Ogawa, Nobutake Shimojo, Akiko Ishii, Akira Tamaoka, Satoru Kawano, Yoshiaki Inoue
Format: Article
Language:English
Published: BMC 2022-06-01
Series:BMC Research Notes
Subjects:
Orexin
Cerebrospinal fluid
Systemic inflammation
Sepsis
Online Access:https://doi.org/10.1186/s13104-022-06121-0

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