Recent advances in drug substance development – prodrug strategies for enhancing the bioavailability and potency of antiviral nucleosides
Bioavailability is a prerequisite for drug activity. In vivo bioavailability (intestinal permeability), linked to drug substance solubility and drug product dissolution, became the basis of Gordon L. Amidon’s Biopharmaceutical Classification System. One method of improving the drug substance’s bi...
Main Author: | Andrzej Kutner |
---|---|
Format: | Article |
Language: | English |
Published: |
Poznan University of Medical Sciences
2023-09-01
|
Series: | Journal of Medical Science |
Subjects: | |
Online Access: | https://jms.ump.edu.pl/index.php/JMS/article/view/878 |
Similar Items
-
An Orally Bioavailable (Mice) Prodrug of Glutathione
by: Daune L. Crankshaw, et al.
Published: (2021-06-01) -
Current prodrug strategies for improving oral absorption of nucleoside analogues
by: Youxi Zhang, et al.
Published: (2014-04-01) -
Advanced Prodrug Strategies in Nucleoside and Non-Nucleoside Antiviral Agents: A Review of the Recent Five Years
by: Hanadi Sinokrot, et al.
Published: (2017-10-01) -
Ester Prodrugs of Levofloxacin to Prevent Chelate Formation in Presence of Aluminium Ion
by: Yorinobu Maeda, et al.
Published: (2023-01-01) -
Advanced prodrug strategies in nucleoside analogues targeting the treatment of gastrointestinal malignancies
by: Xingxing Xu, et al.
Published: (2023-04-01)