Characterization of dengue virus 3'UTR RNA binding proteins in mosquitoes reveals that AeStaufen reduces subgenomic flaviviral RNA in saliva.

Characterization of dengue virus 3'UTR RNA binding proteins in mosquitoes reveals that AeStaufen reduces subgenomic flaviviral RNA in saliva.

Dengue viruses (DENV) are expanding global pathogens that are transmitted through the bite of mosquitoes, mostly Aedes aegypti. As RNA viruses, DENV rely on RNA-binding proteins (RBPs) to complete their life cycle. Alternatively, RBPs can act as restriction factors that prevent DENV multiplication....

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Bibliographic Details
Main Authors: Shih-Chia Yeh, Mayra Diosa-Toro, Wei-Lian Tan, Florian Rachenne, Arthur Hain, Celestia Pei Xuan Yeo, Inès Bribes, Benjamin Wong Wei Xiang, Gayathiri Sathiamoorthy Kannan, Menchie Casayuran Manuel, Dorothée Missé, Yu Keung Mok, Julien Pompon
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2022-09-01
Series:PLoS Pathogens
Online Access:https://doi.org/10.1371/journal.ppat.1010427

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