Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes
Introduction: Mobile phone users and base stations have increased exponentially in recent decades. These expansions have extended worries about the potential risk of long-lasting Radiofrequency Electromagnetic Fields (RF-EMF) exposure on human health and environmental quality. The current study was...
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| Format: | Article |
| Language: | English |
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Mashhad University of Medical Sciences
2023-09-01
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| Series: | Iranian Journal of Medical Physics |
| Subjects: | |
| Online Access: | https://ijmp.mums.ac.ir/article_21104_2fb39d46b79b4770fe9ff32657939f1d.pdf |
| _version_ | 1797209627072397312 |
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| author | Ahmad Khalil Heba Al Naimi Ahmad Alshamali |
| author_facet | Ahmad Khalil Heba Al Naimi Ahmad Alshamali |
| author_sort | Ahmad Khalil |
| collection | DOAJ |
| description | Introduction: Mobile phone users and base stations have increased exponentially in recent decades. These expansions have extended worries about the potential risk of long-lasting Radiofrequency Electromagnetic Fields (RF-EMF) exposure on human health and environmental quality. The current study was designed to explore the cytogenetic consequences of subjecting two biological systems to RF-EMF at a frequency of 1800MHz and a specific absorption rate of 0.27 W/kg.
Material and Methods: Chromosome aberration test (onion meristematic cells) and micronucleus assay (mouse erythrocytes) were used to evaluate the potential cytotoxic and genotoxic effects of the in vivo exposure to RF-EMF at a frequency of 1800 MHz. The two living systems were subjected to RF-EMF for 0, 0.5, 1, 2, and 4 hours daily for seven successive days. We recorded the percent aberrant cells (%Abc), the percentage of micronuclei formation in erythrocytes (%MN), and the percentage of micronucleated polychromatic erythrocytes (%MNPCE).
Results: It was demonstrated that the short- and intermediate-term exposure to RF-EMF may cause a gradual time-dependent boost in root growth. However, significant growth inhibition was observed following 4-hour exposure. Exposure to RF-EMF did not change mitotic indices of onion meristematic cells. Significant increases in Abc, MN, and MNPCE percentages were recorded.
Conclusion: The outcome of this study proposes that unlimited exposure of living organisms to RF-EMF may lead to adverse effects. Therefore, unnecessary use of mobile phones should be avoided. |
| first_indexed | 2024-04-24T09:57:42Z |
| format | Article |
| id | doaj.art-71d9ac1ab89944db978ea33a7ffaeac9 |
| institution | Directory Open Access Journal |
| issn | 2345-3672 |
| language | English |
| last_indexed | 2024-04-24T09:57:42Z |
| publishDate | 2023-09-01 |
| publisher | Mashhad University of Medical Sciences |
| record_format | Article |
| series | Iranian Journal of Medical Physics |
| spelling | doaj.art-71d9ac1ab89944db978ea33a7ffaeac92024-04-14T06:28:24ZengMashhad University of Medical SciencesIranian Journal of Medical Physics2345-36722023-09-0120527328110.22038/ijmp.2022.66419.214221104Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic ErythrocytesAhmad Khalil0Heba Al Naimi1Ahmad Alshamali2Department of Biological Sciences Faculty of Science Yarmouk University Irbid JordanDepartment of Biological Sciences, Yarmouk University, Faculty of Science, Irbid, Jordan.Department of Telecommunication Engineering, Hijjawi Faculty for Engineering Technology, Yarmouk University, Irbid, Jordan.Introduction: Mobile phone users and base stations have increased exponentially in recent decades. These expansions have extended worries about the potential risk of long-lasting Radiofrequency Electromagnetic Fields (RF-EMF) exposure on human health and environmental quality. The current study was designed to explore the cytogenetic consequences of subjecting two biological systems to RF-EMF at a frequency of 1800MHz and a specific absorption rate of 0.27 W/kg. Material and Methods: Chromosome aberration test (onion meristematic cells) and micronucleus assay (mouse erythrocytes) were used to evaluate the potential cytotoxic and genotoxic effects of the in vivo exposure to RF-EMF at a frequency of 1800 MHz. The two living systems were subjected to RF-EMF for 0, 0.5, 1, 2, and 4 hours daily for seven successive days. We recorded the percent aberrant cells (%Abc), the percentage of micronuclei formation in erythrocytes (%MN), and the percentage of micronucleated polychromatic erythrocytes (%MNPCE). Results: It was demonstrated that the short- and intermediate-term exposure to RF-EMF may cause a gradual time-dependent boost in root growth. However, significant growth inhibition was observed following 4-hour exposure. Exposure to RF-EMF did not change mitotic indices of onion meristematic cells. Significant increases in Abc, MN, and MNPCE percentages were recorded. Conclusion: The outcome of this study proposes that unlimited exposure of living organisms to RF-EMF may lead to adverse effects. Therefore, unnecessary use of mobile phones should be avoided.https://ijmp.mums.ac.ir/article_21104_2fb39d46b79b4770fe9ff32657939f1d.pdfallium cepabalb/c mousechromosome aberrationsmicronucleus formationmobile phones |
| spellingShingle | Ahmad Khalil Heba Al Naimi Ahmad Alshamali Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes Iranian Journal of Medical Physics allium cepa balb/c mouse chromosome aberrations micronucleus formation mobile phones |
| title | Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes |
| title_full | Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes |
| title_fullStr | Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes |
| title_full_unstemmed | Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes |
| title_short | Cytotoxicity and Genotoxicity of Radiofrequency Electromagnetic Field in Onion Root Tip Cells and Mouse Polychromatic Erythrocytes |
| title_sort | cytotoxicity and genotoxicity of radiofrequency electromagnetic field in onion root tip cells and mouse polychromatic erythrocytes |
| topic | allium cepa balb/c mouse chromosome aberrations micronucleus formation mobile phones |
| url | https://ijmp.mums.ac.ir/article_21104_2fb39d46b79b4770fe9ff32657939f1d.pdf |
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