Microfluidic hemophilia models using blood from healthy donors

Microfluidic hemophilia models using blood from healthy donors

Abstract Background Microfluidic clotting assays permit drug action studies for hemophilia therapeutics under flow. However, limited availability of patient samples and Inter‐donor variability limit the application of such assays, especially with many patients on prophylaxis. Objective To develop ap...

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Bibliographic Details
Main Authors: Xinren Yu, Karen A. Panckeri, Lacramioara Ivanciu, Rodney M. Camire, Carmen H. Coxon, Adam Cuker, Scott L. Diamond
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
drug evaluation
fibrin
hemophilia
hemostasis
microfluidics
Online Access:https://doi.org/10.1002/rth2.12286

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