A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children
IntroductionEmotion recognition is a core feature of social perception. In particular, perception of dynamic facial emotional expressions is a major feature of the third visual pathway. However, the classical N170 visual evoked signal does not provide a pure correlate of such processing. Indeed, ind...
| Principais autores: | , , , , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | English |
| Publicado em: |
Frontiers Media S.A.
2023-12-01
|
| coleção: | Frontiers in Neuroscience |
| Assuntos: | |
| Acesso em linha: | https://www.frontiersin.org/articles/10.3389/fnins.2023.1295608/full |
| _version_ | 1827581084955574272 |
|---|---|
| author | Daniela Sousa Daniela Sousa Daniela Sousa Ana Ferreira Ana Ferreira Ana Ferreira Diana Rodrigues Diana Rodrigues Helena Catarina Pereira Helena Catarina Pereira Helena Catarina Pereira Joana Amaral Joana Amaral Joana Amaral Joana Crisostomo Joana Crisostomo Joana Crisostomo Marco Simoes Marco Simoes Marco Simoes Marco Simoes Mário Ribeiro Mário Ribeiro Marta Teixeira Marta Teixeira Miguel Castelo-Branco Miguel Castelo-Branco Miguel Castelo-Branco Miguel Castelo-Branco |
| author_facet | Daniela Sousa Daniela Sousa Daniela Sousa Ana Ferreira Ana Ferreira Ana Ferreira Diana Rodrigues Diana Rodrigues Helena Catarina Pereira Helena Catarina Pereira Helena Catarina Pereira Joana Amaral Joana Amaral Joana Amaral Joana Crisostomo Joana Crisostomo Joana Crisostomo Marco Simoes Marco Simoes Marco Simoes Marco Simoes Mário Ribeiro Mário Ribeiro Marta Teixeira Marta Teixeira Miguel Castelo-Branco Miguel Castelo-Branco Miguel Castelo-Branco Miguel Castelo-Branco |
| author_sort | Daniela Sousa |
| collection | DOAJ |
| description | IntroductionEmotion recognition is a core feature of social perception. In particular, perception of dynamic facial emotional expressions is a major feature of the third visual pathway. However, the classical N170 visual evoked signal does not provide a pure correlate of such processing. Indeed, independent component analysis has demonstrated that the N170 component is already active at the time of the P100, and is therefore distorted by early components. Here we implemented, a dynamic face emotional paradigm to isolate a more pure face expression selective N170. We searched for a neural correlate of perception of dynamic facial emotional expressions, by starting with a face baseline from which a facial expression evolved. This allowed for a specific facial expression contrast signal which we aimed to relate with social communication abilities and cortical gamma-aminobutyric acid (GABA) levels.MethodsWe recorded event-related potentials (ERPs) and Magnetic Resonance (MRS) measures in 35 typically developing (TD) children, (10–16 years) sex-matched, during emotion recognition of an avatar morphing/unmorphing from neutral to happy/sad expressions. This task allowed for the elimination of the contribution low-level visual components, in particular the P100, by morphing baseline isoluminant neutral faces into specific expressions, isolating dynamic emotion recognition. Therefore, it was possible to isolate a dynamic face sensitive N170 devoid of interactions with earlier components.ResultsWe found delayed N170 and P300, with a hysteresis type of dependence on stimulus trajectory (morphing/unmorphing), with hemispheric lateralization. The delayed N170 is generated by an extrastriate source, which can be related to the third visual pathway specialized in biological motion processing. GABA levels in visual cortex were related with N170 amplitude and latency and predictive of worse social communication performance (SCQ scores). N170 latencies reflected delayed processing speed of emotional expressions and related to worse social communication scores.DiscussionIn sum, we found a specific N170 electrophysiological signature of dynamic face processing related to social communication abilities and cortical GABA levels. These findings have potential clinical significance supporting the hypothesis of a spectrum of social communication abilities and the identification of a specific face-expression sensitive N170 which can potentially be used in the development of diagnostic and intervention tools. |
| first_indexed | 2024-03-08T22:30:24Z |
| format | Article |
| id | doaj.art-71e1bea408b84056bb548bbc7916cba7 |
| institution | Directory Open Access Journal |
| issn | 1662-453X |
| language | English |
| last_indexed | 2024-03-08T22:30:24Z |
| publishDate | 2023-12-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Neuroscience |
| spelling | doaj.art-71e1bea408b84056bb548bbc7916cba72023-12-18T04:48:03ZengFrontiers Media S.A.Frontiers in Neuroscience1662-453X2023-12-011710.3389/fnins.2023.12956081295608A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in childrenDaniela Sousa0Daniela Sousa1Daniela Sousa2Ana Ferreira3Ana Ferreira4Ana Ferreira5Diana Rodrigues6Diana Rodrigues7Helena Catarina Pereira8Helena Catarina Pereira9Helena Catarina Pereira10Joana Amaral11Joana Amaral12Joana Amaral13Joana Crisostomo14Joana Crisostomo15Joana Crisostomo16Marco Simoes17Marco Simoes18Marco Simoes19Marco Simoes20Mário Ribeiro21Mário Ribeiro22Marta Teixeira23Marta Teixeira24Miguel Castelo-Branco25Miguel Castelo-Branco26Miguel Castelo-Branco27Miguel Castelo-Branco28Coimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalCentre for Informatics and Systems, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalCoimbra Institute for Biomedical Imaging and Translational Research CIBIT, University of Coimbra, Coimbra, PortugalInstitute for Nuclear Sciences Applied to Health ICNAS, University of Coimbra, Coimbra, PortugalFaculty of Medicine, University of Coimbra, Coimbra, PortugalDepartment of Psychology, University of Maastricht, Maastricht, NetherlandsIntroductionEmotion recognition is a core feature of social perception. In particular, perception of dynamic facial emotional expressions is a major feature of the third visual pathway. However, the classical N170 visual evoked signal does not provide a pure correlate of such processing. Indeed, independent component analysis has demonstrated that the N170 component is already active at the time of the P100, and is therefore distorted by early components. Here we implemented, a dynamic face emotional paradigm to isolate a more pure face expression selective N170. We searched for a neural correlate of perception of dynamic facial emotional expressions, by starting with a face baseline from which a facial expression evolved. This allowed for a specific facial expression contrast signal which we aimed to relate with social communication abilities and cortical gamma-aminobutyric acid (GABA) levels.MethodsWe recorded event-related potentials (ERPs) and Magnetic Resonance (MRS) measures in 35 typically developing (TD) children, (10–16 years) sex-matched, during emotion recognition of an avatar morphing/unmorphing from neutral to happy/sad expressions. This task allowed for the elimination of the contribution low-level visual components, in particular the P100, by morphing baseline isoluminant neutral faces into specific expressions, isolating dynamic emotion recognition. Therefore, it was possible to isolate a dynamic face sensitive N170 devoid of interactions with earlier components.ResultsWe found delayed N170 and P300, with a hysteresis type of dependence on stimulus trajectory (morphing/unmorphing), with hemispheric lateralization. The delayed N170 is generated by an extrastriate source, which can be related to the third visual pathway specialized in biological motion processing. GABA levels in visual cortex were related with N170 amplitude and latency and predictive of worse social communication performance (SCQ scores). N170 latencies reflected delayed processing speed of emotional expressions and related to worse social communication scores.DiscussionIn sum, we found a specific N170 electrophysiological signature of dynamic face processing related to social communication abilities and cortical GABA levels. These findings have potential clinical significance supporting the hypothesis of a spectrum of social communication abilities and the identification of a specific face-expression sensitive N170 which can potentially be used in the development of diagnostic and intervention tools.https://www.frontiersin.org/articles/10.3389/fnins.2023.1295608/fullsocial cognitionsocial communicationdynamic emotional expressionsevent-related potentialsGABAtypically developing children |
| spellingShingle | Daniela Sousa Daniela Sousa Daniela Sousa Ana Ferreira Ana Ferreira Ana Ferreira Diana Rodrigues Diana Rodrigues Helena Catarina Pereira Helena Catarina Pereira Helena Catarina Pereira Joana Amaral Joana Amaral Joana Amaral Joana Crisostomo Joana Crisostomo Joana Crisostomo Marco Simoes Marco Simoes Marco Simoes Marco Simoes Mário Ribeiro Mário Ribeiro Marta Teixeira Marta Teixeira Miguel Castelo-Branco Miguel Castelo-Branco Miguel Castelo-Branco Miguel Castelo-Branco A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children Frontiers in Neuroscience social cognition social communication dynamic emotional expressions event-related potentials GABA typically developing children |
| title | A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children |
| title_full | A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children |
| title_fullStr | A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children |
| title_full_unstemmed | A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children |
| title_short | A neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma-aminobutyric acid levels in children |
| title_sort | neurophysiological signature of dynamic emotion recognition associated with social communication skills and cortical gamma aminobutyric acid levels in children |
| topic | social cognition social communication dynamic emotional expressions event-related potentials GABA typically developing children |
| url | https://www.frontiersin.org/articles/10.3389/fnins.2023.1295608/full |
| work_keys_str_mv | AT danielasousa aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT danielasousa aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT danielasousa aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT anaferreira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT anaferreira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT anaferreira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT dianarodrigues aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT dianarodrigues aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT helenacatarinapereira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT helenacatarinapereira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT helenacatarinapereira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanaamaral aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanaamaral aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanaamaral aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanacrisostomo aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanacrisostomo aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanacrisostomo aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marioribeiro aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marioribeiro aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT martateixeira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT martateixeira aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco aneurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT danielasousa neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT danielasousa neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT danielasousa neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT anaferreira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT anaferreira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT anaferreira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT dianarodrigues neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT dianarodrigues neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT helenacatarinapereira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT helenacatarinapereira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT helenacatarinapereira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanaamaral neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanaamaral neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanaamaral neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanacrisostomo neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanacrisostomo neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT joanacrisostomo neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marcosimoes neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marioribeiro neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT marioribeiro neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT martateixeira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT martateixeira neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren AT miguelcastelobranco neurophysiologicalsignatureofdynamicemotionrecognitionassociatedwithsocialcommunicationskillsandcorticalgammaaminobutyricacidlevelsinchildren |