Low-Dose Resveratrol Inhibits RIPK3-Mediated Necroptosis and Delays the Onset of Age-Related Hearing Loss

Low-Dose Resveratrol Inhibits RIPK3-Mediated Necroptosis and Delays the Onset of Age-Related Hearing Loss

Background: To investigate the pathophysiology of age-related hearing loss (ARHL) and the mechanism of resveratrol (RSV) in prevention and treatment of ARHL.Methods: C57BL/6 mice of different ages were used in this study. Auditory brainstem response (ABR) was performed to assess hearing and identify...

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Bibliographic Details
Main Authors: Zeyin Yang, Yan Zhang, Shuling Yang, Yongqing Ding, Yan Qu
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
age-related hearing loss
presbycusis
resveratrol
necroptosis
ripk3
aging cochlea
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.910308/full

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