Virally Suppressed People Living with HIV Who Use Opioids Have Diminished Latency Reversal

Virally Suppressed People Living with HIV Who Use Opioids Have Diminished Latency Reversal

Of the 12 million people who inject drugs worldwide, 13% live with HIV. Whether opioid use impacts HIV pathogenesis and latency is an outstanding question. To gain insight into whether opioid use influences the proviral landscape and latent HIV reservoir, we performed intact proviral DNA assays (IPD...

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Bibliographic Details
Main Authors: Binita Basukala, Sarah Rossi, Sally Bendiks, Natalia Gnatienko, Gregory Patts, Evgeny Krupitsky, Dmitry Lioznov, Kaku So-Armah, Manish Sagar, Christine Cheng, Andrew J. Henderson
Format: Article
Language:English
Published: MDPI AG 2023-02-01
Series:Viruses
Subjects:
opioid use
HIV pathogenesis
HIV latency
Online Access:https://www.mdpi.com/1999-4915/15/2/415

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