Rosmarinic acid alleviates acetaminophen-induced hepatotoxicity by targeting Nrf2 and NEK7-NLRP3 signaling pathway

Rosmarinic acid (RA) is a natural polyphenol with various biological activities, such as anti-oxidative, anti-fibrotic, and hepatoprotective properties. The objective of this study was to investigate the protective effect of RA against acetaminophen (APAP)-induced hepatotoxicity (AILI) and explore t...

Полное описание

Библиографические подробности
Главные авторы: Yang Yao, Rong Li, Dan Liu, Lihui Long, Na He
Формат: Статья
Язык:English
Опубликовано: Elsevier 2022-08-01
Серии:Ecotoxicology and Environmental Safety
Предметы:
Online-ссылка:http://www.sciencedirect.com/science/article/pii/S0147651322006133