Angiosarcoma of the mandible

Angiosarcoma is a rare malignancy of vascular endothelium which may arise from either blood or lymphatic vessels. These tumors are aggressive with a tendency to recur locally and also have a high rate of lymph node and systemic metastases. Angiosarcomas occur more frequently in skin and soft tissue....

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Bibliographic Details
Main Authors: M C Shashikanth, Neelkamal Sharda, I M Ali, U Deepak, Sheeba Mohindra
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2008-01-01
Series:Journal of Indian Academy of Oral Medicine and Radiology
Subjects:
Online Access:http://www.jiaomr.in/article.asp?issn=0972-1363;year=2008;volume=20;issue=1;spage=19;epage=22;aulast=Shashikanth
Description
Summary:Angiosarcoma is a rare malignancy of vascular endothelium which may arise from either blood or lymphatic vessels. These tumors are aggressive with a tendency to recur locally and also have a high rate of lymph node and systemic metastases. Angiosarcomas occur more frequently in skin and soft tissue. Occurrence of a primary or metastatic angiosarcoma in the oral cavity is extremely rare. The purpose of this article is to document a case of primary angiosarcoma in the right mandible of a 20 year old woman. The tumor presented as a rapidly enlarging lobulated soft tissue mass which was associated with an irregular radiolytic defect in the right mandible. Histological features of the lesion were suggestive of a high grade angiosarcoma. The patient was successfully treated with a combination therapy involving surgery and chemotherapy. There were no signs of tumor recurrence or metastasis after one and a half year of follow up.
ISSN:0972-1363
0975-1572