CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES

The decision to install cardiac resynchronization device in patients may be associated not with the apparent clini- cal effectiveness, but for other reasons that require medical consultation. This may be due to the need to create a «bridge» to heart transplantation (HT), for example. In order to pre...

Full description

Bibliographic Details
Main Authors: E. N. Ostroumov, E. D. Kotina, V. A. Shmyrov, V. V. Slobodyanik, V. V. Tonkoshkurova, N. P. Mozeiko, I. M. Ilyinski, D. V. Shumakov
Format: Article
Language:Russian
Published: Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov 2012-09-01
Series:Vestnik Transplantologii i Iskusstvennyh Organov
Subjects:
Online Access:https://journal.transpl.ru/vtio/article/view/192
_version_ 1797872146869911552
author E. N. Ostroumov
E. D. Kotina
V. A. Shmyrov
V. V. Slobodyanik
V. V. Tonkoshkurova
N. P. Mozeiko
I. M. Ilyinski
D. V. Shumakov
author_facet E. N. Ostroumov
E. D. Kotina
V. A. Shmyrov
V. V. Slobodyanik
V. V. Tonkoshkurova
N. P. Mozeiko
I. M. Ilyinski
D. V. Shumakov
author_sort E. N. Ostroumov
collection DOAJ
description The decision to install cardiac resynchronization device in patients may be associated not with the apparent clini- cal effectiveness, but for other reasons that require medical consultation. This may be due to the need to create a «bridge» to heart transplantation (HT), for example. In order to predict the outcome of CRT, we observed 54 pa- tients with HF, III–IV functional class NYHA, on the waiting list for HT. Cardiomyopathy was diagnosed in 36 patients, various forms of ischemic heart disease was diagnosed in 17 patients, all with the ECG determined left bundle branch block with QRS complex duration of less than 120 ms. All patients performed gated SPECT before and after CRT with standard methods of research. LVEF at baseline did not exceed 35%. Monitoring was continued for 2 years after the start of the CRT. The results were divided into two groups. Group 1 consisted of patients who need HT for 2 years, in spite of the CRT (11 patients). Group 2 consisted of patients who have an increase in LVEF of at least 10% after CRT (28 patients). When comparing the initial and final performance with the help of the Main- Whitney in both groups, most significant differences were found in the assessment of myocardial perfusion relation- ships lateral walls of LV and RV. The decrease in the ratio between the level of perfusion of the lateral walls of LV and RV < 2,0 reduces the effectiveness of CRT, and within two years, there occured a need for a heart transplant.
first_indexed 2024-04-10T00:54:15Z
format Article
id doaj.art-71e9148e1f1949e3a1367b85c4497309
institution Directory Open Access Journal
issn 1995-1191
language Russian
last_indexed 2024-04-10T00:54:15Z
publishDate 2012-09-01
publisher Federal Research Center of Transplantology and Artificial Organs named after V.I.Shumakov
record_format Article
series Vestnik Transplantologii i Iskusstvennyh Organov
spelling doaj.art-71e9148e1f1949e3a1367b85c44973092023-03-13T10:37:19ZrusFederal Research Center of Transplantology and Artificial Organs named after V.I.ShumakovVestnik Transplantologii i Iskusstvennyh Organov1995-11912012-09-01143606810.15825/1995-1191-2012-3-60-68135CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLESE. N. Ostroumov0E. D. Kotina1V. A. Shmyrov2V. V. Slobodyanik3V. V. Tonkoshkurova4N. P. Mozeiko5I. M. Ilyinski6D. V. Shumakov7Academician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowSaint-Petersburg State University, St. PetersburgSaint-Petersburg State University, St. PetersburgAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowAcademician V.I. Shumakov Federal Research Center of Transplantology and Artificial Organs, MoscowThe decision to install cardiac resynchronization device in patients may be associated not with the apparent clini- cal effectiveness, but for other reasons that require medical consultation. This may be due to the need to create a «bridge» to heart transplantation (HT), for example. In order to predict the outcome of CRT, we observed 54 pa- tients with HF, III–IV functional class NYHA, on the waiting list for HT. Cardiomyopathy was diagnosed in 36 patients, various forms of ischemic heart disease was diagnosed in 17 patients, all with the ECG determined left bundle branch block with QRS complex duration of less than 120 ms. All patients performed gated SPECT before and after CRT with standard methods of research. LVEF at baseline did not exceed 35%. Monitoring was continued for 2 years after the start of the CRT. The results were divided into two groups. Group 1 consisted of patients who need HT for 2 years, in spite of the CRT (11 patients). Group 2 consisted of patients who have an increase in LVEF of at least 10% after CRT (28 patients). When comparing the initial and final performance with the help of the Main- Whitney in both groups, most significant differences were found in the assessment of myocardial perfusion relation- ships lateral walls of LV and RV. The decrease in the ratio between the level of perfusion of the lateral walls of LV and RV < 2,0 reduces the effectiveness of CRT, and within two years, there occured a need for a heart transplant.https://journal.transpl.ru/vtio/article/view/192cardiac resynchronization therapygated spectthe ratio of the level of perfusion of the lateral walls of lv and rv.
spellingShingle E. N. Ostroumov
E. D. Kotina
V. A. Shmyrov
V. V. Slobodyanik
V. V. Tonkoshkurova
N. P. Mozeiko
I. M. Ilyinski
D. V. Shumakov
CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES
Vestnik Transplantologii i Iskusstvennyh Organov
cardiac resynchronization therapy
gated spect
the ratio of the level of perfusion of the lateral walls of lv and rv.
title CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES
title_full CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES
title_fullStr CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES
title_full_unstemmed CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES
title_short CARDIAC RESYNCHRONIZATION THERAPY AND MYOCARDIAL PERFUSION OF THE LEFT AND RIGHT VENTRICLES
title_sort cardiac resynchronization therapy and myocardial perfusion of the left and right ventricles
topic cardiac resynchronization therapy
gated spect
the ratio of the level of perfusion of the lateral walls of lv and rv.
url https://journal.transpl.ru/vtio/article/view/192
work_keys_str_mv AT enostroumov cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT edkotina cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT vashmyrov cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT vvslobodyanik cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT vvtonkoshkurova cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT npmozeiko cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT imilyinski cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles
AT dvshumakov cardiacresynchronizationtherapyandmyocardialperfusionoftheleftandrightventricles