ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER
Analysis of association, between several DNA repair gene polymorphisms and the level of chromosomal aberrations (CAs) in lymphocytes was performed in two groups: a group of 215 patients with lung cancer and a control group of 152 donors. In the group patient with lung cancer the level of CAs shows a...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | Russian |
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Scientific Сentre for Family Health and Human Reproduction Problems
2012-05-01
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| Series: | Acta Biomedica Scientifica |
| Subjects: | |
| Online Access: | https://www.actabiomedica.ru/jour/article/view/900 |
| _version_ | 1826853646194704384 |
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| author | V. I. Minina M. L. Bakanova J. A. Savchenko A. A. Timopheyeva T. P. Anosova V. A. Titov N. E. Verghbizkaja A. N. Glushkov |
| author_facet | V. I. Minina M. L. Bakanova J. A. Savchenko A. A. Timopheyeva T. P. Anosova V. A. Titov N. E. Verghbizkaja A. N. Glushkov |
| author_sort | V. I. Minina |
| collection | DOAJ |
| description | Analysis of association, between several DNA repair gene polymorphisms and the level of chromosomal aberrations (CAs) in lymphocytes was performed in two groups: a group of 215 patients with lung cancer and a control group of 152 donors. In the group patient with lung cancer the level of CAs shows a significant increase in the carrier of genotypes: XPD TG and XPD GG vs XPD TT. In the control group level of CAs shows a significant increase in the carrier of genotype ADPRT ТС vs ТТ. |
| first_indexed | 2024-03-08T12:23:07Z |
| format | Article |
| id | doaj.art-71eb0a0fb3df4ccaa10b1ac060646d9b |
| institution | Directory Open Access Journal |
| issn | 2541-9420 2587-9596 |
| language | Russian |
| last_indexed | 2025-02-16T17:30:30Z |
| publishDate | 2012-05-01 |
| publisher | Scientific Сentre for Family Health and Human Reproduction Problems |
| record_format | Article |
| series | Acta Biomedica Scientifica |
| spelling | doaj.art-71eb0a0fb3df4ccaa10b1ac060646d9b2025-01-27T16:48:37ZrusScientific Сentre for Family Health and Human Reproduction ProblemsActa Biomedica Scientifica2541-94202587-95962012-05-0103(2)121124846ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCERV. I. Minina0M. L. Bakanova1J. A. Savchenko2A. A. Timopheyeva3T. P. Anosova4V. A. Titov5N. E. Verghbizkaja6A. N. Glushkov7Institute of Human Ecology SB RAMSInstitute of Human Ecology SB RAMSInstitute of Human Ecology SB RAMSInstitute of Human Ecology SB RAMSInstitute of Human Ecology SB RAMSRegional Clinical Oncology DyspensaryPathologoanatomic bureauInstitute of Human Ecology SB RAMSAnalysis of association, between several DNA repair gene polymorphisms and the level of chromosomal aberrations (CAs) in lymphocytes was performed in two groups: a group of 215 patients with lung cancer and a control group of 152 donors. In the group patient with lung cancer the level of CAs shows a significant increase in the carrier of genotypes: XPD TG and XPD GG vs XPD TT. In the control group level of CAs shows a significant increase in the carrier of genotype ADPRT ТС vs ТТ.https://www.actabiomedica.ru/jour/article/view/900lung cancerdna repair gene |
| spellingShingle | V. I. Minina M. L. Bakanova J. A. Savchenko A. A. Timopheyeva T. P. Anosova V. A. Titov N. E. Verghbizkaja A. N. Glushkov ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER Acta Biomedica Scientifica lung cancer dna repair gene |
| title | ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER |
| title_full | ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER |
| title_fullStr | ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER |
| title_full_unstemmed | ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER |
| title_short | ASSOCIATION OF DNA REPAIR GENE POLYMORPHISM WITH CHROMOSOMAL ABERRATIONS IN THE BLOOD LYMPHOCYTES OF PATIENTS WITH LUNG CANCER |
| title_sort | association of dna repair gene polymorphism with chromosomal aberrations in the blood lymphocytes of patients with lung cancer |
| topic | lung cancer dna repair gene |
| url | https://www.actabiomedica.ru/jour/article/view/900 |
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