Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases
Summary: Background & aims: Inadequate knowledge and intake of a balance diet is a contributing factor of micronutrient deficiencies in developing countries. Phytic acid contributes in inhibiting the bioavailability of some micronutrients. In spite of the anti-nutritional effect of phytic acid,...
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| Format: | Article |
| Language: | English |
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Elsevier
2019-12-01
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| Series: | Clinical Nutrition Experimental |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2352939319301216 |
| _version_ | 1819112939266768896 |
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| author | Ibrahim Abdulwaliyu Shefiat Olayemi Arekemase Judy Atabat Adudu Musa Latayo Batari Mercy Nwakamaswor Egbule Stanley Irobekhian Reuben Okoduwa |
| author_facet | Ibrahim Abdulwaliyu Shefiat Olayemi Arekemase Judy Atabat Adudu Musa Latayo Batari Mercy Nwakamaswor Egbule Stanley Irobekhian Reuben Okoduwa |
| author_sort | Ibrahim Abdulwaliyu |
| collection | DOAJ |
| description | Summary: Background & aims: Inadequate knowledge and intake of a balance diet is a contributing factor of micronutrient deficiencies in developing countries. Phytic acid contributes in inhibiting the bioavailability of some micronutrients. In spite of the anti-nutritional effect of phytic acid, it is known to exhibit some medicinal effects. This study investigated the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases. Methods: Relevant scientific literatures from the major databases such as Pubmed, Medline and Google Scholar. The keywords searched and reviewed in this study were phytic acid, anti-nutrients, minerals, diseases and plants. Results: The published peer reviewed literatures searched showed that phytic acid, though an anti-nutrient, plays an indispensable role directly or indirectly in several disease conditions. It exhibits antioxidant function, a property that qualifies it to possess multiple medicinal values like: anti-diabetic, anticancer, anti-inflammatory properties to mention a few. Its chelating property affects the absorption and toxicities associated with essential and nonessential heavy metals, a scenario that could prevent neurodegenerative diseases such as Alzheimer's, Parkinson diseases and other related diseases. Conclusion: The medicinal values of phytic acid outweighed its negative impact. Hence, there is critical need for developing countries to improve on the dietary pattern of its people in addition to nutrition education. Keywords: Phytic acid, Minerals, Anti-Nutrients, Plants, Diseases |
| first_indexed | 2024-12-22T04:21:28Z |
| format | Article |
| id | doaj.art-71ece0d0b7fe49a6ab3b63a39bd9aac1 |
| institution | Directory Open Access Journal |
| issn | 2352-9393 |
| language | English |
| last_indexed | 2024-12-22T04:21:28Z |
| publishDate | 2019-12-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Clinical Nutrition Experimental |
| spelling | doaj.art-71ece0d0b7fe49a6ab3b63a39bd9aac12022-12-21T18:39:15ZengElsevierClinical Nutrition Experimental2352-93932019-12-01284261Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseasesIbrahim Abdulwaliyu0Shefiat Olayemi Arekemase1Judy Atabat Adudu2Musa Latayo Batari3Mercy Nwakamaswor Egbule4Stanley Irobekhian Reuben Okoduwa5Scientific and Industrial Research Department, National Research Institute for Chemical Technology, Zaria, NigeriaPetrochemical and Allied Department, National Research Institute for Chemical Technology, Zaria, NigeriaScientific and Industrial Research Department, National Research Institute for Chemical Technology, Zaria, NigeriaScientific and Industrial Research Department, National Research Institute for Chemical Technology, Zaria, NigeriaDepartment of Biochemistry, Babcock University, Ilishan-Remo, NigeriaDirectorate of Research and Development, Nigerian Institute of Leather and Science Technology, Zaria, Nigeria; Corresponding author. Infohealth Awareness Department, SIRONigeria Global Limited, Abuja, Nigeria.Summary: Background & aims: Inadequate knowledge and intake of a balance diet is a contributing factor of micronutrient deficiencies in developing countries. Phytic acid contributes in inhibiting the bioavailability of some micronutrients. In spite of the anti-nutritional effect of phytic acid, it is known to exhibit some medicinal effects. This study investigated the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases. Methods: Relevant scientific literatures from the major databases such as Pubmed, Medline and Google Scholar. The keywords searched and reviewed in this study were phytic acid, anti-nutrients, minerals, diseases and plants. Results: The published peer reviewed literatures searched showed that phytic acid, though an anti-nutrient, plays an indispensable role directly or indirectly in several disease conditions. It exhibits antioxidant function, a property that qualifies it to possess multiple medicinal values like: anti-diabetic, anticancer, anti-inflammatory properties to mention a few. Its chelating property affects the absorption and toxicities associated with essential and nonessential heavy metals, a scenario that could prevent neurodegenerative diseases such as Alzheimer's, Parkinson diseases and other related diseases. Conclusion: The medicinal values of phytic acid outweighed its negative impact. Hence, there is critical need for developing countries to improve on the dietary pattern of its people in addition to nutrition education. Keywords: Phytic acid, Minerals, Anti-Nutrients, Plants, Diseaseshttp://www.sciencedirect.com/science/article/pii/S2352939319301216 |
| spellingShingle | Ibrahim Abdulwaliyu Shefiat Olayemi Arekemase Judy Atabat Adudu Musa Latayo Batari Mercy Nwakamaswor Egbule Stanley Irobekhian Reuben Okoduwa Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases Clinical Nutrition Experimental |
| title | Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases |
| title_full | Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases |
| title_fullStr | Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases |
| title_full_unstemmed | Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases |
| title_short | Investigation of the medicinal significance of phytic acid as an indispensable anti-nutrient in diseases |
| title_sort | investigation of the medicinal significance of phytic acid as an indispensable anti nutrient in diseases |
| url | http://www.sciencedirect.com/science/article/pii/S2352939319301216 |
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