The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature
Background: Positron emission tomography (PET) scan is a non-invasive, complicated and expensive medical imaging technology used for diagnosis and treatment of various diseases including cancers. This study aimed to evaluate the safety and effectiveness of this technology. Methods: The major medical...
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Isfahan University of Medical Sciences
2012-02-01
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| Series: | مجله دانشکده پزشکی اصفهان |
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| Online Access: | http://jims.mui.ac.ir/index.php/jims/article/view/1282 |
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| author | Hamid Ravaghi Ali Akbari Sari Sima Sarvari Mohammad Reza Mobinizadeh |
| author_facet | Hamid Ravaghi Ali Akbari Sari Sima Sarvari Mohammad Reza Mobinizadeh |
| author_sort | Hamid Ravaghi |
| collection | DOAJ |
| description | Background: Positron emission tomography (PET) scan is a non-invasive, complicated and expensive medical imaging technology used for diagnosis and treatment of various diseases including cancers. This study aimed to evaluate the safety and effectiveness of this technology.
Methods: The major medical electronic databases including Cochrane Library, Google Scholar, MEDLINE and IranMedex were searched. The studies that compared PET-scan with other diagnostic methods in terms of sensitivity, specificity and safety were considered in this review.
Findings: PET-scan has been found to be a non-invasive and safe procedure for diagnosing metastatic NSCLC with a sensitivity and specificity of 74-95% and 81-97%, respectively. On the other hand, the sensitivity and specificity of computed tomography (CT) scan have been reported as 60-67% and 73-77%, respectively. The corresponding values for mediastinoscopy have been 78% and 100%. In lymphoma, the specificity and sensitivity of PET-scan (90% and 79-100%, respectively) have been higher than those of gamma scan. Although PET-scan is not an appropriate method for screening and diagnosis of cancer, it can contribute to staging and follow-up processes in cases of NSCLC and lymphoma. This technology adds 0.046 years (about 17 days) to the patient's life.
Conclusion: PET-scan is a safe technology that has better diagnostic performance in comparison with similar technologies. The application of this method in staging and follow-up of NSCLC and lymphoma can prevent unnecessary surgeries and add a few years to the lives of patients. |
| first_indexed | 2024-03-12T09:51:19Z |
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| id | doaj.art-71ed3847948e4ab3b5284039aab6551f |
| institution | Directory Open Access Journal |
| issn | 1027-7595 1735-854X |
| language | fas |
| last_indexed | 2024-03-12T09:51:19Z |
| publishDate | 2012-02-01 |
| publisher | Isfahan University of Medical Sciences |
| record_format | Article |
| series | مجله دانشکده پزشکی اصفهان |
| spelling | doaj.art-71ed3847948e4ab3b5284039aab6551f2023-09-02T12:29:01ZfasIsfahan University of Medical Sciencesمجله دانشکده پزشکی اصفهان1027-75951735-854X2012-02-012916724472456835The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of LiteratureHamid Ravaghi0Ali Akbari Sari1Sima Sarvari2Mohammad Reza Mobinizadeh3Assistant Professor, Department of Health Service Management, School of Management and Medical Information Services, Tehran University of Medical Sciences, Tehran, IranAssistant Professor, Department of Health Management and Economics, School of Public Health, And Knowledge Utilization Research Center, Tehran University of Medical Sciences, Tehran, IranMedical Lecturer, Medical College, Shantou University, ChinaHealth Technology Assessment (HTA) Office, Deputy of Curative Affairs, Ministry of Health and Medical Education, Tehran, IranBackground: Positron emission tomography (PET) scan is a non-invasive, complicated and expensive medical imaging technology used for diagnosis and treatment of various diseases including cancers. This study aimed to evaluate the safety and effectiveness of this technology. Methods: The major medical electronic databases including Cochrane Library, Google Scholar, MEDLINE and IranMedex were searched. The studies that compared PET-scan with other diagnostic methods in terms of sensitivity, specificity and safety were considered in this review. Findings: PET-scan has been found to be a non-invasive and safe procedure for diagnosing metastatic NSCLC with a sensitivity and specificity of 74-95% and 81-97%, respectively. On the other hand, the sensitivity and specificity of computed tomography (CT) scan have been reported as 60-67% and 73-77%, respectively. The corresponding values for mediastinoscopy have been 78% and 100%. In lymphoma, the specificity and sensitivity of PET-scan (90% and 79-100%, respectively) have been higher than those of gamma scan. Although PET-scan is not an appropriate method for screening and diagnosis of cancer, it can contribute to staging and follow-up processes in cases of NSCLC and lymphoma. This technology adds 0.046 years (about 17 days) to the patient's life. Conclusion: PET-scan is a safe technology that has better diagnostic performance in comparison with similar technologies. The application of this method in staging and follow-up of NSCLC and lymphoma can prevent unnecessary surgeries and add a few years to the lives of patients.http://jims.mui.ac.ir/index.php/jims/article/view/1282PET-scanNSCLCLymphomaImaging |
| spellingShingle | Hamid Ravaghi Ali Akbari Sari Sima Sarvari Mohammad Reza Mobinizadeh The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature مجله دانشکده پزشکی اصفهان PET-scan NSCLC Lymphoma Imaging |
| title | The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature |
| title_full | The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature |
| title_fullStr | The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature |
| title_full_unstemmed | The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature |
| title_short | The Effectiveness of PET-Scan in Diagnosis and Treatment of Non-Small Cell Lung Carcinoma (NSCLC) and Lymphoma: A Comprehensive Review of Literature |
| title_sort | effectiveness of pet scan in diagnosis and treatment of non small cell lung carcinoma nsclc and lymphoma a comprehensive review of literature |
| topic | PET-scan NSCLC Lymphoma Imaging |
| url | http://jims.mui.ac.ir/index.php/jims/article/view/1282 |
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