Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: Protection by diosgenin and l-deprenyl

Increased vulnerability of ApoE4 neurons to HIV proteins and opiates: Protection by diosgenin and l-deprenyl

Human immunodeficiency virus (HIV) infection continues to rise in drug-abusing populations and causes a dementing illness in a subset of individuals. Factors contributing to the development of dementia in this population remain unknown. We found that HIV-infected individuals with the E4 allele of Ap...

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Bibliographic Details
Main Authors: Jadwiga Turchan-Cholewo, Yiling Liu, Suzanne Gartner, Rollie Reid, Chunfa Jie, Xuejun Peng, Kuey Chu C. Chen, Ashok Chauhan, Norman Haughey, Roy Cutler, Mark P. Mattson, Carlos Pardo, Katherine Conant, Ned Sacktor, Justin C. McArthur, Kurt F. Hauser, Chandra Gairola, Avindra Nath
Format: Article
Language:English
Published: Elsevier 2006-07-01
Series:Neurobiology of Disease
Subjects:
Drug abuse
Genetics
HIV
Tat
Opiates
Neuroprotection
Online Access:http://www.sciencedirect.com/science/article/pii/S0969996106000374

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