Mesenchymal stem cell-derived extracellular vesicles transfer miR-598 to inhibit the growth and metastasis of non-small-cell lung cancer by targeting THBS2

Abstract Non-small-cell lung cancer (NSCLC) is the subtype of lung cancer, which accounts for about 85% of diagnosed lung cancer cases, and is without any effective therapy. Emerging evidence has revealed microRNA-598 (miR-598) as potential therapeutic target and diagnostic marker of NSCLC. In the p...

Full description

Bibliographic Details
Main Authors: Xuebo Li, Fan Wu
Format: Article
Language:English
Published: Nature Publishing Group 2023-01-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-022-01283-z