Magnificamide, a β-Defensin-Like Peptide from the Mucus of the Sea Anemone <i>Heteractis magnifica</i>, Is a Strong Inhibitor of Mammalian α-Amylases

Magnificamide, a β-Defensin-Like Peptide from the Mucus of the Sea Anemone <i>Heteractis magnifica</i>, Is a Strong Inhibitor of Mammalian α-Amylases

Sea anemones&#8217; venom is rich in peptides acting on different biological targets, mainly on cytoplasmic membranes and ion channels. These animals are also a source of pancreatic &#945;-amylase inhibitors, which have the ability to control the glucose level in the blood and can be used fo...

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Bibliographic Details
Main Authors: Oksana Sintsova, Irina Gladkikh, Aleksandr Kalinovskii, Elena Zelepuga, Margarita Monastyrnaya, Natalia Kim, Lyudmila Shevchenko, Steve Peigneur, Jan Tytgat, Emma Kozlovskaya, Elena Leychenko
Format: Article
Language:English
Published: MDPI AG 2019-09-01
Series:Marine Drugs
Subjects:
Cnidaria
sea anemones
venom
amylase inhibitors
defensin
diabetes
Online Access:https://www.mdpi.com/1660-3397/17/10/542

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