Does an Apple a Day Also Keep the Microbes Away? The Interplay Between Diet, Microbiota, and Host Defense Peptides at the Intestinal Mucosal Barrier

Does an Apple a Day Also Keep the Microbes Away? The Interplay Between Diet, Microbiota, and Host Defense Peptides at the Intestinal Mucosal Barrier

A crucial mechanism of intestinal defense includes the production and secretion of host defense peptides (HDPs). HDPs control pathogens and commensals at the intestinal interface by direct killing, by sequestering vital ions, or by causing bacterial cells to aggregate in the mucus layer. Accordingly...

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Bibliographic Details
Main Authors: Fabiola Puértolas-Balint, Bjoern O. Schroeder
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Immunology
Subjects:
antimicrobial peptides
defensins
microbiota
diet
prebiotics and probiotics
high-fat diet
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2020.01164/full

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