The budding yeast GSK-3 homologue Mck1 is an essential component of the spindle position checkpoint

The spindle position checkpoint (SPOC) is a mitotic surveillance mechanism in Saccharomyces cerevisiae that prevents cells from completing mitosis in response to spindle misalignment, thereby contributing to genomic integrity. The kinase Kin4, one of the most downstream SPOC components, is essential...

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Bibliographic Details
Main Authors: Siddhi Rathi, Irem Polat, Gislene Pereira
Format: Article
Language:English
Published: The Royal Society 2022-11-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/10.1098/rsob.220203