A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis
<i>Objectives</i>: The aim of this study was to compare the values of total antioxidant capacity (TAC), catalase (CAT) and glutathione peroxidase (GPX) in the saliva of children and young teenagers with and without gingivitis. <i>Materials and Methods</i>: A total of 120 chil...
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MDPI AG
2021-06-01
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| Online Access: | https://www.mdpi.com/1648-9144/57/6/569 |
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| author | Olivera Tričković Janjić Tatjana Cvetković Branislava Stojković Raša Mladenović Mila Janjić Ranković |
| author_facet | Olivera Tričković Janjić Tatjana Cvetković Branislava Stojković Raša Mladenović Mila Janjić Ranković |
| author_sort | Olivera Tričković Janjić |
| collection | DOAJ |
| description | <i>Objectives</i>: The aim of this study was to compare the values of total antioxidant capacity (TAC), catalase (CAT) and glutathione peroxidase (GPX) in the saliva of children and young teenagers with and without gingivitis. <i>Materials and Methods</i>: A total of 120 children and young teenagers of the mean age of 12.2 participated in the research. Gingival condition was assessed using the Löe and Silness Gingival Index. The subjects were divided into groups of those without gingivitis and those with gingivitis. Samples of unstimulated saliva were collected, and TAC, CAT and GPX were determined spectrophotometrically. <i>Results</i>: By comparing the values of TAC, CAT and GPX in subjects with and without gingivitis, significantly lower values of TAC (<i>p</i> < 0.001) and CAT (<i>p</i> < 0.001) were observed in the group of subjects with gingivitis. The correlation analysis of these values showed a positive correlation in groups of subjects not suffering from gingival inflammation and those with gingival inflammation. <i>Conclusions</i>: The study showed significantly lower values of TAC and CAT in the saliva of subjects with gingivitis. This indicates their possible role as a potential biomarker in the early diagnosis and expression of periodontal disease in children and young teenagers. |
| first_indexed | 2024-03-10T10:45:53Z |
| format | Article |
| id | doaj.art-71f4895a6b854698a4075d309b2db486 |
| institution | Directory Open Access Journal |
| issn | 1010-660X 1648-9144 |
| language | English |
| last_indexed | 2024-03-10T10:45:53Z |
| publishDate | 2021-06-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Medicina |
| spelling | doaj.art-71f4895a6b854698a4075d309b2db4862023-11-21T22:38:01ZengMDPI AGMedicina1010-660X1648-91442021-06-0157656910.3390/medicina57060569A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without GingivitisOlivera Tričković Janjić0Tatjana Cvetković1Branislava Stojković2Raša Mladenović3Mila Janjić Ranković4Department of Preventive and Pediatric Dentistry, Faculty of Medicine, University of Niš, 18000 Niš, SerbiaDepartment of Biochemistry, Faculty of Medicine, University of Niš, 18000 Niš, SerbiaDepartment of Preventive and Pediatric Dentistry, Faculty of Medicine, University of Niš, 18000 Niš, SerbiaDepartment for Dentistry, Faculty of Medicine, University of Priština, 38220 Kosovska Mitrovica, SerbiaDepartment of Orthodontics and Dentofacial Orthopedics, University Hospital, LMU Munich, 80336 Munich, Germany<i>Objectives</i>: The aim of this study was to compare the values of total antioxidant capacity (TAC), catalase (CAT) and glutathione peroxidase (GPX) in the saliva of children and young teenagers with and without gingivitis. <i>Materials and Methods</i>: A total of 120 children and young teenagers of the mean age of 12.2 participated in the research. Gingival condition was assessed using the Löe and Silness Gingival Index. The subjects were divided into groups of those without gingivitis and those with gingivitis. Samples of unstimulated saliva were collected, and TAC, CAT and GPX were determined spectrophotometrically. <i>Results</i>: By comparing the values of TAC, CAT and GPX in subjects with and without gingivitis, significantly lower values of TAC (<i>p</i> < 0.001) and CAT (<i>p</i> < 0.001) were observed in the group of subjects with gingivitis. The correlation analysis of these values showed a positive correlation in groups of subjects not suffering from gingival inflammation and those with gingival inflammation. <i>Conclusions</i>: The study showed significantly lower values of TAC and CAT in the saliva of subjects with gingivitis. This indicates their possible role as a potential biomarker in the early diagnosis and expression of periodontal disease in children and young teenagers.https://www.mdpi.com/1648-9144/57/6/569childrenteenagersgingivitissalivatotal antioxidant capacitycatalase |
| spellingShingle | Olivera Tričković Janjić Tatjana Cvetković Branislava Stojković Raša Mladenović Mila Janjić Ranković A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis Medicina children teenagers gingivitis saliva total antioxidant capacity catalase |
| title | A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis |
| title_full | A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis |
| title_fullStr | A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis |
| title_full_unstemmed | A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis |
| title_short | A Comparative Study of Antioxidative Activity of Saliva in Children and Young Teenagers with and without Gingivitis |
| title_sort | comparative study of antioxidative activity of saliva in children and young teenagers with and without gingivitis |
| topic | children teenagers gingivitis saliva total antioxidant capacity catalase |
| url | https://www.mdpi.com/1648-9144/57/6/569 |
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