Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions
Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of...
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Format: | Article |
Language: | English |
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Korean Society of Gastrointestinal Endoscopy
2015-11-01
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Series: | Clinical Endoscopy |
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Online Access: | http://www.e-ce.org/upload/pdf/ce-48-6-511.pdf |
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author | Sang Kil Lee |
author_facet | Sang Kil Lee |
author_sort | Sang Kil Lee |
collection | DOAJ |
description | Confocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of CLE are more obvious in esophageal disease, including Barrett’s esophagus. Currently, this technology has been adapted to the diagnosis and surveillance of Barrett’s esophagus and related neoplasia. Standard white light endoscopy is the primary tool for gastric cancer screening. Currently, the only method available to precisely diagnose these lesions is upper endoscopy with an appropriate biopsy. A recent study showed that CLE could characterize dysplasia or cancer and identify the risk factors for gastric cancer, such as intestinal metaplasia and the presence of Helicobacter pylori in vivo, although fewer studies on CLE were performed on the stomach than on Barrett’s esophagus and other esophageal diseases. However, the application of CLE to routine clinical endoscopy continues to be refined. This review focused on the usefulness and future prospects of CLE for gastric premalignant and malignant lesions. |
first_indexed | 2024-03-09T08:16:42Z |
format | Article |
id | doaj.art-71f5b1b65de544f9bd8dfac152033111 |
institution | Directory Open Access Journal |
issn | 2234-2400 2234-2443 |
language | English |
last_indexed | 2024-03-09T08:16:42Z |
publishDate | 2015-11-01 |
publisher | Korean Society of Gastrointestinal Endoscopy |
record_format | Article |
series | Clinical Endoscopy |
spelling | doaj.art-71f5b1b65de544f9bd8dfac1520331112023-12-02T22:06:50ZengKorean Society of Gastrointestinal EndoscopyClinical Endoscopy2234-24002234-24432015-11-0148651151510.5946/ce.2015.48.6.5116794Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant LesionsSang Kil LeeConfocal laser endomicroscopy (CLE) is a new technology enabling endoscopists to visualize tissue at the cellular level. CLE has the fundamental potential to provide a histologic diagnosis, and may theoretically replace or reduce the need for performing biopsy for histology. The clinical benefits of CLE are more obvious in esophageal disease, including Barrett’s esophagus. Currently, this technology has been adapted to the diagnosis and surveillance of Barrett’s esophagus and related neoplasia. Standard white light endoscopy is the primary tool for gastric cancer screening. Currently, the only method available to precisely diagnose these lesions is upper endoscopy with an appropriate biopsy. A recent study showed that CLE could characterize dysplasia or cancer and identify the risk factors for gastric cancer, such as intestinal metaplasia and the presence of Helicobacter pylori in vivo, although fewer studies on CLE were performed on the stomach than on Barrett’s esophagus and other esophageal diseases. However, the application of CLE to routine clinical endoscopy continues to be refined. This review focused on the usefulness and future prospects of CLE for gastric premalignant and malignant lesions.http://www.e-ce.org/upload/pdf/ce-48-6-511.pdfConfocal laser endomicroscopyStomach neoplasmsGastric intestinal metaplasia |
spellingShingle | Sang Kil Lee Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions Clinical Endoscopy Confocal laser endomicroscopy Stomach neoplasms Gastric intestinal metaplasia |
title | Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions |
title_full | Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions |
title_fullStr | Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions |
title_full_unstemmed | Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions |
title_short | Usefulness and Future Prospects of Confocal Laser Endomicroscopy for Gastric Premalignant and Malignant Lesions |
title_sort | usefulness and future prospects of confocal laser endomicroscopy for gastric premalignant and malignant lesions |
topic | Confocal laser endomicroscopy Stomach neoplasms Gastric intestinal metaplasia |
url | http://www.e-ce.org/upload/pdf/ce-48-6-511.pdf |
work_keys_str_mv | AT sangkillee usefulnessandfutureprospectsofconfocallaserendomicroscopyforgastricpremalignantandmalignantlesions |