Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome
Objective: During surgery on low-grade gliomas (LGG), reliable data relevant to the primary motor cortex (M1) for the face area are lacking. We analyzed the impact of tumor removal within the M1 face area on neurological deficits. Methods: We included LGG patients with resection within the M1 face a...
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MDPI AG
2023-01-01
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| Series: | Cancers |
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| Online Access: | https://www.mdpi.com/2072-6694/15/3/781 |
| _version_ | 1797624966820134912 |
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| author | Katharina Lutz Levin Häni Cédric Kissling Andreas Raabe Philippe Schucht Kathleen Seidel |
| author_facet | Katharina Lutz Levin Häni Cédric Kissling Andreas Raabe Philippe Schucht Kathleen Seidel |
| author_sort | Katharina Lutz |
| collection | DOAJ |
| description | Objective: During surgery on low-grade gliomas (LGG), reliable data relevant to the primary motor cortex (M1) for the face area are lacking. We analyzed the impact of tumor removal within the M1 face area on neurological deficits. Methods: We included LGG patients with resection within the M1 face area between May 2012 and November 2019. The primary endpoint was postoperative facial motor function. Secondary endpoints were postoperative aphasia, dysarthria, and dysphagia. Surgery was performed either with the awake protocol or under anesthesia with continuous dynamic mapping. The alarm criteria were speech arrest or a mapping threshold of 3 mA or less. Resection was completed in five patients. The resection was stopped due to the alarm criteria in three patients and for other reasons (vascular supply, patient performance) in four patients. A total of 66.7% (<i>n</i> = 8) presented with new-onset facial paresis (62.5% left LGG) and 41.7% (<i>n</i> = 5) with aphasia (all left LGG) postoperatively. After one year, all eight patients had recovered from the facial paresis. Tumor removal within the M1 face area was not associated with permanent facial motor deficits. |
| first_indexed | 2024-03-11T09:50:09Z |
| format | Article |
| id | doaj.art-71f662af79aa4a7291bb6b75edaf49cf |
| institution | Directory Open Access Journal |
| issn | 2072-6694 |
| language | English |
| last_indexed | 2024-03-11T09:50:09Z |
| publishDate | 2023-01-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Cancers |
| spelling | doaj.art-71f662af79aa4a7291bb6b75edaf49cf2023-11-16T16:17:07ZengMDPI AGCancers2072-66942023-01-0115378110.3390/cancers15030781Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological OutcomeKatharina Lutz0Levin Häni1Cédric Kissling2Andreas Raabe3Philippe Schucht4Kathleen Seidel5Department of Neurosurgery, Inselspital, Bern University Hospital, 3010 Bern, SwitzerlandDepartment of Neurosurgery, Inselspital, Bern University Hospital, 3010 Bern, SwitzerlandDepartment of Neurosurgery, Inselspital, Bern University Hospital, 3010 Bern, SwitzerlandDepartment of Neurosurgery, Inselspital, Bern University Hospital, 3010 Bern, SwitzerlandDepartment of Neurosurgery, Inselspital, Bern University Hospital, 3010 Bern, SwitzerlandDepartment of Neurosurgery, Inselspital, Bern University Hospital, 3010 Bern, SwitzerlandObjective: During surgery on low-grade gliomas (LGG), reliable data relevant to the primary motor cortex (M1) for the face area are lacking. We analyzed the impact of tumor removal within the M1 face area on neurological deficits. Methods: We included LGG patients with resection within the M1 face area between May 2012 and November 2019. The primary endpoint was postoperative facial motor function. Secondary endpoints were postoperative aphasia, dysarthria, and dysphagia. Surgery was performed either with the awake protocol or under anesthesia with continuous dynamic mapping. The alarm criteria were speech arrest or a mapping threshold of 3 mA or less. Resection was completed in five patients. The resection was stopped due to the alarm criteria in three patients and for other reasons (vascular supply, patient performance) in four patients. A total of 66.7% (<i>n</i> = 8) presented with new-onset facial paresis (62.5% left LGG) and 41.7% (<i>n</i> = 5) with aphasia (all left LGG) postoperatively. After one year, all eight patients had recovered from the facial paresis. Tumor removal within the M1 face area was not associated with permanent facial motor deficits.https://www.mdpi.com/2072-6694/15/3/781low-grade gliomaglioma surgeryface motor cortexintraoperative neurophysiological monitoringGTRmotor evoked potentials |
| spellingShingle | Katharina Lutz Levin Häni Cédric Kissling Andreas Raabe Philippe Schucht Kathleen Seidel Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome Cancers low-grade glioma glioma surgery face motor cortex intraoperative neurophysiological monitoring GTR motor evoked potentials |
| title | Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome |
| title_full | Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome |
| title_fullStr | Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome |
| title_full_unstemmed | Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome |
| title_short | Resection of Low-Grade Gliomas in the Face Area of the Primary Motor Cortex and Neurological Outcome |
| title_sort | resection of low grade gliomas in the face area of the primary motor cortex and neurological outcome |
| topic | low-grade glioma glioma surgery face motor cortex intraoperative neurophysiological monitoring GTR motor evoked potentials |
| url | https://www.mdpi.com/2072-6694/15/3/781 |
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