ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

ASAR lncRNAs control DNA replication timing through interactions with multiple hnRNP/RNA binding proteins

ASARs are a family of very-long noncoding RNAs that control replication timing on individual human autosomes, and are essential for chromosome stability. The eight known ASAR lncRNAs remain closely associated with their parent chromosomes. Analysis of RNA-protein interaction data (from ENCODE) revea...

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Bibliographic Details
Main Authors: Mathew Thayer, Michael B Heskett, Leslie G Smith, Paul T Spellman, Phillip A Yates
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2024-06-01
Series:eLife
Subjects:
Replication
RNA binding
chromosome
long non-coding RNA
ASAR
XIST
Online Access:https://elifesciences.org/articles/95898

Internet

https://elifesciences.org/articles/95898

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