Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review
Guillain-Barré syndrome (GBS) is a severe peripheral neuroinflammatory demyelinating disease characterized by symmetrical progressive limb weakness, which can be accompanied by cranial nerve and sensory disturbances. There is usually a history of bacterial or viral infection prior to onset. GBS is r...
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| Format: | Article |
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MDPI AG
2023-03-01
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| Series: | Brain Sciences |
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| Online Access: | https://www.mdpi.com/2076-3425/13/4/527 |
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| author | Jinsheng Liu Feng Tang Xinjun Chen Zhiqiang Li |
| author_facet | Jinsheng Liu Feng Tang Xinjun Chen Zhiqiang Li |
| author_sort | Jinsheng Liu |
| collection | DOAJ |
| description | Guillain-Barré syndrome (GBS) is a severe peripheral neuroinflammatory demyelinating disease characterized by symmetrical progressive limb weakness, which can be accompanied by cranial nerve and sensory disturbances. There is usually a history of bacterial or viral infection prior to onset. GBS is rarely seen after traumatic brain injury (TBI). We report a case of a 66-year-old male patient who presented with dilated pupils, followed by respiratory failure and symmetrical quadriplegia during a conservative treatment for TBI. He was eventually diagnosed with GBS and was treated with intravenous immunoglobulin, followed by rehabilitation therapy with a good recovery. We summarize previous similar cases and analyze possible causes. It is suggested that the possibility of GBS should be considered when unexplained symptoms occurred in patients with TBI, such as respiratory failure, dilated pupils, and limb weakness. |
| first_indexed | 2024-03-11T05:12:00Z |
| format | Article |
| id | doaj.art-71fe2042431b48308e2a21732c0df79b |
| institution | Directory Open Access Journal |
| issn | 2076-3425 |
| language | English |
| last_indexed | 2024-03-11T05:12:00Z |
| publishDate | 2023-03-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Brain Sciences |
| spelling | doaj.art-71fe2042431b48308e2a21732c0df79b2023-11-17T18:31:30ZengMDPI AGBrain Sciences2076-34252023-03-0113452710.3390/brainsci13040527Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature ReviewJinsheng Liu0Feng Tang1Xinjun Chen2Zhiqiang Li3Department of Neurosurgery, Zhongnan Hospital, Wuhan University, Wuhan 430062, ChinaDepartment of Neurosurgery, Zhongnan Hospital, Wuhan University, Wuhan 430062, ChinaDepartment of Neurosurgery, Zhongnan Hospital, Wuhan University, Wuhan 430062, ChinaDepartment of Neurosurgery, Zhongnan Hospital, Wuhan University, Wuhan 430062, ChinaGuillain-Barré syndrome (GBS) is a severe peripheral neuroinflammatory demyelinating disease characterized by symmetrical progressive limb weakness, which can be accompanied by cranial nerve and sensory disturbances. There is usually a history of bacterial or viral infection prior to onset. GBS is rarely seen after traumatic brain injury (TBI). We report a case of a 66-year-old male patient who presented with dilated pupils, followed by respiratory failure and symmetrical quadriplegia during a conservative treatment for TBI. He was eventually diagnosed with GBS and was treated with intravenous immunoglobulin, followed by rehabilitation therapy with a good recovery. We summarize previous similar cases and analyze possible causes. It is suggested that the possibility of GBS should be considered when unexplained symptoms occurred in patients with TBI, such as respiratory failure, dilated pupils, and limb weakness.https://www.mdpi.com/2076-3425/13/4/527Guillain-Barré syndrometraumatic brain injuryelectromyographycase report |
| spellingShingle | Jinsheng Liu Feng Tang Xinjun Chen Zhiqiang Li Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review Brain Sciences Guillain-Barré syndrome traumatic brain injury electromyography case report |
| title | Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review |
| title_full | Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review |
| title_fullStr | Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review |
| title_full_unstemmed | Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review |
| title_short | Guillain-Barré Syndrome with Incomplete Oculomotor Nerve Palsy after Traumatic Brain Injury: Case Report and Literature Review |
| title_sort | guillain barre syndrome with incomplete oculomotor nerve palsy after traumatic brain injury case report and literature review |
| topic | Guillain-Barré syndrome traumatic brain injury electromyography case report |
| url | https://www.mdpi.com/2076-3425/13/4/527 |
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