Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report.
Most people with toxoplasmosis infection are asymptomatic. Cerebral toxoplasmosis in HIV patient represents poor prognostic determinant, but treatable if early treatment is initiated. A case of delayed diagnosis of cerebraltoxoplasmosis is presented.A 27-year-old man presented with one-sided facial...
| Main Authors: | , , |
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| Format: | Article |
| Language: | English |
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Tehran University of Medical Sciences
2023-03-01
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| Series: | Case Reports in Clinical Practice |
| Subjects: | |
| Online Access: | https://crcp.tums.ac.ir/index.php/crcp/article/view/689 |
| _version_ | 1797840412146139136 |
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| author | Norly Salleh Rusli Zaim Siti Rodiah Udin |
| author_facet | Norly Salleh Rusli Zaim Siti Rodiah Udin |
| author_sort | Norly Salleh |
| collection | DOAJ |
| description |
Most people with toxoplasmosis infection are asymptomatic. Cerebral toxoplasmosis in HIV patient represents poor prognostic determinant, but treatable if early treatment is initiated. A case of delayed diagnosis of cerebraltoxoplasmosis is presented.A 27-year-old man presented with one-sided facial numbness and treated as Bell’s Palsy. Later he developed slurred speech. Contrast enhanced CT brain showed left frontal temporal hypodense lesion, leptomeningeal enhancement and perilesional oedema. Steroid was started. Four days later, he presented with decreased responsiveness. Retroviral was detected and diagnosis changed to opportunistic brain infection. He died after 3 days. Toxoplasmosis IgG antibodies turned out positive.In diagnosing cerebral toxoplasmosis, clinical presentation and examination are as important as laboratory testing and radiological imaging.
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| first_indexed | 2024-04-09T16:14:41Z |
| format | Article |
| id | doaj.art-7200a4ac13134cfd8f447ecef5c5ed88 |
| institution | Directory Open Access Journal |
| issn | 2538-2683 2538-2691 |
| language | English |
| last_indexed | 2024-04-09T16:14:41Z |
| publishDate | 2023-03-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Case Reports in Clinical Practice |
| spelling | doaj.art-7200a4ac13134cfd8f447ecef5c5ed882023-04-24T06:43:36ZengTehran University of Medical SciencesCase Reports in Clinical Practice2538-26832538-26912023-03-017610.18502/crcp.v7i6.12273Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report.Norly Salleh0Rusli Zaim1Siti Rodiah Udin2Department of Surgery, Hospital Segamat, KM 6, Jalan Genuang, 85000 Segamat, Johor, Malaysia.AND Satellite Clinical Research Centre, Hospital Segamat, KM 6, Jalan Genuang, 85000 Segamat, Johor, MalaysiaDrDepartment of Radiology, Hospital Segamat, KM 6, Jalan Genuang, 85000 Segamat, Johor, Malaysia.Department of Surgery, Hospital Segamat, KM 6, Jalan Genuang, 85000 Segamat, Johor, Malaysia Most people with toxoplasmosis infection are asymptomatic. Cerebral toxoplasmosis in HIV patient represents poor prognostic determinant, but treatable if early treatment is initiated. A case of delayed diagnosis of cerebraltoxoplasmosis is presented.A 27-year-old man presented with one-sided facial numbness and treated as Bell’s Palsy. Later he developed slurred speech. Contrast enhanced CT brain showed left frontal temporal hypodense lesion, leptomeningeal enhancement and perilesional oedema. Steroid was started. Four days later, he presented with decreased responsiveness. Retroviral was detected and diagnosis changed to opportunistic brain infection. He died after 3 days. Toxoplasmosis IgG antibodies turned out positive.In diagnosing cerebral toxoplasmosis, clinical presentation and examination are as important as laboratory testing and radiological imaging. https://crcp.tums.ac.ir/index.php/crcp/article/view/689Cerebral toxoplasmosisToxoplasmosis; PatientImmunocompromisedCase report |
| spellingShingle | Norly Salleh Rusli Zaim Siti Rodiah Udin Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. Case Reports in Clinical Practice Cerebral toxoplasmosis Toxoplasmosis; Patient Immunocompromised Case report |
| title | Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. |
| title_full | Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. |
| title_fullStr | Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. |
| title_full_unstemmed | Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. |
| title_short | Cerebral Toxoplasmosis in a Previously Fit Individual – Pitfalls in Management – A Case Report. |
| title_sort | cerebral toxoplasmosis in a previously fit individual pitfalls in management a case report |
| topic | Cerebral toxoplasmosis Toxoplasmosis; Patient Immunocompromised Case report |
| url | https://crcp.tums.ac.ir/index.php/crcp/article/view/689 |
| work_keys_str_mv | AT norlysalleh cerebraltoxoplasmosisinapreviouslyfitindividualpitfallsinmanagementacasereport AT ruslizaim cerebraltoxoplasmosisinapreviouslyfitindividualpitfallsinmanagementacasereport AT sitirodiahudin cerebraltoxoplasmosisinapreviouslyfitindividualpitfallsinmanagementacasereport |