P29 MECHANISMS OF VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION INDUCED HYPERTENSION

P29 MECHANISMS OF VASCULAR ENDOTHELIAL GROWTH FACTOR INHIBITION INDUCED HYPERTENSION

Introduction: Drugs targeting Vascular Endothelial Growth Factor (VEGF) signaling pathway are approved therapies for cancer. Unfortunately, VEGF inhibitors lead to hypertension in 30-80% patients. Reduced nitric oxide synthase activity and increased vascular resistance have been proposed as potentia...

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Main Authors: Kaisa Maki-Petaja, Adam McGeoch, Lucy Yang, Annette Hubsch, Carmel McEniery, Fraz Mir, Parag Gajendragadkar, Nicola Ramenatte, Gayathri Anandappa, Christoph Brune, Yoeri Boink, Carola Bibiane-Schonlieb, Paul Meyer, Simon Bond, Ian Wilkinson, Duncan Jodrell, Joseph Cheriyan
Format: Article
Language:English
Published: BMC 2018-12-01
Series:Artery Research
Online Access:https://www.atlantis-press.com/article/125930040/view

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