A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference

Fast and accurate point-of-care testing (POCT) of infectious diseases is crucial for diminishing the pandemic miseries. To fight the pandemic coronavirus disease 2019 (COVID-19), numerous interesting electrochemical point-of-care (POC) tests have been evolved to rapidly identify the causal organism...

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Main Authors: Gokul Chandra Biswas, Swapnila Choudhury, Mohammad Mahbub Rabbani, Jagotamoy Das
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Chemosensors
Subjects:
Online Access:https://www.mdpi.com/2227-9040/10/7/269
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author Gokul Chandra Biswas
Swapnila Choudhury
Mohammad Mahbub Rabbani
Jagotamoy Das
author_facet Gokul Chandra Biswas
Swapnila Choudhury
Mohammad Mahbub Rabbani
Jagotamoy Das
author_sort Gokul Chandra Biswas
collection DOAJ
description Fast and accurate point-of-care testing (POCT) of infectious diseases is crucial for diminishing the pandemic miseries. To fight the pandemic coronavirus disease 2019 (COVID-19), numerous interesting electrochemical point-of-care (POC) tests have been evolved to rapidly identify the causal organism SARS-CoV-2 virus, its nucleic acid and antigens, and antibodies of the patients. Many of those electrochemical biosensors are impressive in terms of miniaturization, mass production, ease of use, and speed of test, and they could be recommended for future applications in pandemic-like circumstances. On the other hand, self-diagnosis, sensitivity, specificity, surface chemistry, electrochemical components, device configuration, portability, small analyzers, and other features of the tests can yet be improved. Therefore, this report reviews the developmental trend of electrochemical POC tests (i.e., test platforms and features) reported for the rapid diagnosis of COVID-19 and correlates any significant advancements with relevant references. POCTs incorporating microfluidic/plastic chips, paper devices, nanomaterial-aided platforms, smartphone integration, self-diagnosis, and epidemiological reporting attributes are also surfed to help with future pandemic preparedness. This review especially screens the low-cost and easily affordable setups so that management of pandemic disease becomes faster and easier. Overall, the review is a wide-ranging package for finding appropriate strategies of electrochemical POCT targeting pandemic infectious disease detection.
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spelling doaj.art-720562ae09b645b88a5fb17dbda59e242023-12-03T14:50:28ZengMDPI AGChemosensors2227-90402022-07-0110726910.3390/chemosensors10070269A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a ReferenceGokul Chandra Biswas0Swapnila Choudhury1Mohammad Mahbub Rabbani2Jagotamoy Das3Department of Genetic Engineering and Biotechnology, School of Life Sciences, Shahjalal University of Science and Technology, Sylhet 3114, BangladeshDepartment of Genetic Engineering and Biotechnology, Faculty of Life and Earth Science, Jagannath University, Dhaka 1100, BangladeshDepartment of Chemistry, American International University-Bangladesh (AIUB), Dhaka 1229, BangladeshDepartment of Chemistry, Northwestern University, 2170 Campus Dr., Evanston, IL 60208, USAFast and accurate point-of-care testing (POCT) of infectious diseases is crucial for diminishing the pandemic miseries. To fight the pandemic coronavirus disease 2019 (COVID-19), numerous interesting electrochemical point-of-care (POC) tests have been evolved to rapidly identify the causal organism SARS-CoV-2 virus, its nucleic acid and antigens, and antibodies of the patients. Many of those electrochemical biosensors are impressive in terms of miniaturization, mass production, ease of use, and speed of test, and they could be recommended for future applications in pandemic-like circumstances. On the other hand, self-diagnosis, sensitivity, specificity, surface chemistry, electrochemical components, device configuration, portability, small analyzers, and other features of the tests can yet be improved. Therefore, this report reviews the developmental trend of electrochemical POC tests (i.e., test platforms and features) reported for the rapid diagnosis of COVID-19 and correlates any significant advancements with relevant references. POCTs incorporating microfluidic/plastic chips, paper devices, nanomaterial-aided platforms, smartphone integration, self-diagnosis, and epidemiological reporting attributes are also surfed to help with future pandemic preparedness. This review especially screens the low-cost and easily affordable setups so that management of pandemic disease becomes faster and easier. Overall, the review is a wide-ranging package for finding appropriate strategies of electrochemical POCT targeting pandemic infectious disease detection.https://www.mdpi.com/2227-9040/10/7/269electrochemical biosensorpoint-of-care testingdiagnostic toolsCOVID-19SARS-CoV-2 detectionportable analyzers
spellingShingle Gokul Chandra Biswas
Swapnila Choudhury
Mohammad Mahbub Rabbani
Jagotamoy Das
A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference
Chemosensors
electrochemical biosensor
point-of-care testing
diagnostic tools
COVID-19
SARS-CoV-2 detection
portable analyzers
title A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference
title_full A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference
title_fullStr A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference
title_full_unstemmed A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference
title_short A Review on Potential Electrochemical Point-of-Care Tests Targeting Pandemic Infectious Disease Detection: COVID-19 as a Reference
title_sort review on potential electrochemical point of care tests targeting pandemic infectious disease detection covid 19 as a reference
topic electrochemical biosensor
point-of-care testing
diagnostic tools
COVID-19
SARS-CoV-2 detection
portable analyzers
url https://www.mdpi.com/2227-9040/10/7/269
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