HIF-1-Dependent Induction of β3 Adrenoceptor: Evidence from the Mouse Retina

HIF-1-Dependent Induction of β3 Adrenoceptor: Evidence from the Mouse Retina

A major player in the homeostatic response to hypoxia is the hypoxia-inducible factor (HIF)-1 that transactivates a number of genes involved in neovessel proliferation in response to low oxygen tension. In the retina, hypoxia overstimulates β-adrenoceptors (β-ARs) which play a key role in the format...

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Bibliographic Details
Main Authors: Rosario Amato, Francesco Pisani, Emiliano Laudadio, Maurizio Cammalleri, Martina Lucchesi, Silvia Marracci, Luca Filippi, Roberta Galeazzi, Maria Svelto, Massimo Dal Monte, Paola Bagnoli
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
oxygen-induced retinopathy
HIF-1 binding site
computational analysis
ChIP-qPCR
gene expression
Online Access:https://www.mdpi.com/2073-4409/11/8/1271

Internet

https://www.mdpi.com/2073-4409/11/8/1271

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