Competing scaffolding proteins determine capsid size during mobilization of Staphylococcus aureus pathogenicity islands

Competing scaffolding proteins determine capsid size during mobilization of Staphylococcus aureus pathogenicity islands

Staphylococcus aureus pathogenicity islands (SaPIs), such as SaPI1, exploit specific helper bacteriophages, like 80α, for their high frequency mobilization, a process termed ‘molecular piracy’. SaPI1 redirects the helper’s assembly pathway to form small capsids that can only accommodate the smaller...

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Bibliographic Details
Main Authors: Altaira D Dearborn, Erin A Wall, James L Kizziah, Laura Klenow, Laura K Parker, Keith A Manning, Michael S Spilman, John M Spear, Gail E Christie, Terje Dokland
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2017-10-01
Series:eLife
Subjects:
bacteriophage 80alpha
S. aureus pathogenicity island 1 (SaPI1)
cryo-electron microscopy
virus structure and assembly
three-dimensional reconstruction
Staphylococcus aureus
Online Access:https://elifesciences.org/articles/30822

Internet

https://elifesciences.org/articles/30822

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