LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.

Approximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated ris...

Full description

Bibliographic Details
Main Authors: J P Dinis Teixeira, Mário J D S Santos, Patrícia Soares, Luísa de Azevedo, Patrícia Barbosa, Andreia Vilas Boas, João V Cordeiro, Sónia Dias, Marta Fonseca, Ana Rita Goes, Maria João Lobão, Marta Moniz, Sofia Nóbrega, André Peralta-Santos, Víctor Ramos, João Victor Rocha, António Carlos da Silva, Maria da Luz Brazão, Andreia Leite, Carla Nunes
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2023-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0285051
_version_ 1827948695506649088
author J P Dinis Teixeira
Mário J D S Santos
Patrícia Soares
Luísa de Azevedo
Patrícia Barbosa
Andreia Vilas Boas
João V Cordeiro
Sónia Dias
Marta Fonseca
Ana Rita Goes
Maria João Lobão
Marta Moniz
Sofia Nóbrega
André Peralta-Santos
Víctor Ramos
João Victor Rocha
António Carlos da Silva
Maria da Luz Brazão
Andreia Leite
Carla Nunes
author_facet J P Dinis Teixeira
Mário J D S Santos
Patrícia Soares
Luísa de Azevedo
Patrícia Barbosa
Andreia Vilas Boas
João V Cordeiro
Sónia Dias
Marta Fonseca
Ana Rita Goes
Maria João Lobão
Marta Moniz
Sofia Nóbrega
André Peralta-Santos
Víctor Ramos
João Victor Rocha
António Carlos da Silva
Maria da Luz Brazão
Andreia Leite
Carla Nunes
author_sort J P Dinis Teixeira
collection DOAJ
description Approximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COVID-19. The LOCUS study was designed to clarify the PCC's burden and associated risk factors. LOCUS is a multi-component study that encompasses three complementary building blocks. The "Cardiovascular and respiratory events following COVID-19" component is set to estimate the incidence of cardiovascular and respiratory events after COVID-19 in eight Portuguese hospitals via electronic health records consultation. The "Physical and mental symptoms following COVID-19" component aims to address the community prevalence of self-reported PCC symptoms through a questionnaire-based approach. Finally, the "Treating and living with Post COVID-19 Condition" component will employ semi-structured interviews and focus groups to characterise reported experiences of using or working in healthcare and community services for the treatment of PCC symptoms. This multi-component study represents an innovative approach to exploring the health consequences of PCC. Its results are expected to provide a key contribution to the optimisation of healthcare services design.
first_indexed 2024-04-09T12:58:12Z
format Article
id doaj.art-72112dd7005d44dfbc9d6f059c7532e8
institution Directory Open Access Journal
issn 1932-6203
language English
last_indexed 2024-04-09T12:58:12Z
publishDate 2023-01-01
publisher Public Library of Science (PLoS)
record_format Article
series PLoS ONE
spelling doaj.art-72112dd7005d44dfbc9d6f059c7532e82023-05-13T05:31:32ZengPublic Library of Science (PLoS)PLoS ONE1932-62032023-01-01184e028505110.1371/journal.pone.0285051LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.J P Dinis TeixeiraMário J D S SantosPatrícia SoaresLuísa de AzevedoPatrícia BarbosaAndreia Vilas BoasJoão V CordeiroSónia DiasMarta FonsecaAna Rita GoesMaria João LobãoMarta MonizSofia NóbregaAndré Peralta-SantosVíctor RamosJoão Victor RochaAntónio Carlos da SilvaMaria da Luz BrazãoAndreia LeiteCarla NunesApproximately 10% of patients experience symptoms of Post COVID-19 Condition (PCC) after a SARS-CoV-2 infection. Akin acute COVID-19, PCC may impact a multitude of organs and systems, such as the cardiovascular, respiratory, musculoskeletal, and neurological systems. The frequency and associated risk factors of PCC are still unclear among both community and hospital settings in individuals with a history of COVID-19. The LOCUS study was designed to clarify the PCC's burden and associated risk factors. LOCUS is a multi-component study that encompasses three complementary building blocks. The "Cardiovascular and respiratory events following COVID-19" component is set to estimate the incidence of cardiovascular and respiratory events after COVID-19 in eight Portuguese hospitals via electronic health records consultation. The "Physical and mental symptoms following COVID-19" component aims to address the community prevalence of self-reported PCC symptoms through a questionnaire-based approach. Finally, the "Treating and living with Post COVID-19 Condition" component will employ semi-structured interviews and focus groups to characterise reported experiences of using or working in healthcare and community services for the treatment of PCC symptoms. This multi-component study represents an innovative approach to exploring the health consequences of PCC. Its results are expected to provide a key contribution to the optimisation of healthcare services design.https://doi.org/10.1371/journal.pone.0285051
spellingShingle J P Dinis Teixeira
Mário J D S Santos
Patrícia Soares
Luísa de Azevedo
Patrícia Barbosa
Andreia Vilas Boas
João V Cordeiro
Sónia Dias
Marta Fonseca
Ana Rita Goes
Maria João Lobão
Marta Moniz
Sofia Nóbrega
André Peralta-Santos
Víctor Ramos
João Victor Rocha
António Carlos da Silva
Maria da Luz Brazão
Andreia Leite
Carla Nunes
LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.
PLoS ONE
title LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.
title_full LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.
title_fullStr LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.
title_full_unstemmed LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.
title_short LOCUS (LOng Covid-Understanding Symptoms, events and use of services in Portugal): A three-component study protocol.
title_sort locus long covid understanding symptoms events and use of services in portugal a three component study protocol
url https://doi.org/10.1371/journal.pone.0285051
work_keys_str_mv AT jpdinisteixeira locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT mariojdssantos locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT patriciasoares locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT luisadeazevedo locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT patriciabarbosa locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT andreiavilasboas locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT joaovcordeiro locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT soniadias locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT martafonseca locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT anaritagoes locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT mariajoaolobao locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT martamoniz locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT sofianobrega locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT andreperaltasantos locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT victorramos locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT joaovictorrocha locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT antoniocarlosdasilva locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT mariadaluzbrazao locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT andreialeite locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol
AT carlanunes locuslongcovidunderstandingsymptomseventsanduseofservicesinportugalathreecomponentstudyprotocol