A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications

Monitoring the vital signs and physiological responses of the human body in daily activities is particularly useful for the early diagnosis and prevention of cardiovascular diseases. Here, we proposed a wireless and flexible biosensor patch for continuous and longitudinal monitoring of different phy...

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Main Authors: Duc Tri Phan, Cong Hoan Nguyen, Thuy Dung Pham Nguyen, Le Hai Tran, Sumin Park, Jaeyeop Choi, Byeong-il Lee, Junghwan Oh
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Biosensors
Subjects:
Online Access:https://www.mdpi.com/2079-6374/12/3/139
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author Duc Tri Phan
Cong Hoan Nguyen
Thuy Dung Pham Nguyen
Le Hai Tran
Sumin Park
Jaeyeop Choi
Byeong-il Lee
Junghwan Oh
author_facet Duc Tri Phan
Cong Hoan Nguyen
Thuy Dung Pham Nguyen
Le Hai Tran
Sumin Park
Jaeyeop Choi
Byeong-il Lee
Junghwan Oh
author_sort Duc Tri Phan
collection DOAJ
description Monitoring the vital signs and physiological responses of the human body in daily activities is particularly useful for the early diagnosis and prevention of cardiovascular diseases. Here, we proposed a wireless and flexible biosensor patch for continuous and longitudinal monitoring of different physiological signals, including body temperature, blood pressure (BP), and electrocardiography. Moreover, these modalities for tracking body movement and GPS locations for emergency rescue have been included in biosensor devices. We optimized the flexible patch design with high mechanical stretchability and compatibility that can provide reliable and long-term attachment to the curved skin surface. Regarding smart healthcare applications, this research presents an Internet of Things-connected healthcare platform consisting of a smartphone application, website service, database server, and mobile gateway. The IoT platform has the potential to reduce the demand for medical resources and enhance the quality of healthcare services. To further address the advances in non-invasive continuous BP monitoring, an optimized deep learning architecture with one-channel electrocardiogram signals is introduced. The performance of the BP estimation model was verified using an independent dataset; this experimental result satisfied the Association for the Advancement of Medical Instrumentation, and the British Hypertension Society standards for BP monitoring devices. The experimental results demonstrated the practical application of the wireless and flexible biosensor patch for continuous physiological signal monitoring with Internet of Medical Things-connected healthcare applications.
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spelling doaj.art-7214857f63f74b96ba1918d1f406c62f2023-11-30T20:53:52ZengMDPI AGBiosensors2079-63742022-02-0112313910.3390/bios12030139A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things ApplicationsDuc Tri Phan0Cong Hoan Nguyen1Thuy Dung Pham Nguyen2Le Hai Tran3Sumin Park4Jaeyeop Choi5Byeong-il Lee6Junghwan Oh7Industry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaDepartment of Smart Healthcare, Pukyong National University, Busan 48513, KoreaIndustry 4.0 Convergence Bionics Engineering, Pukyong National University, Busan 48513, KoreaMonitoring the vital signs and physiological responses of the human body in daily activities is particularly useful for the early diagnosis and prevention of cardiovascular diseases. Here, we proposed a wireless and flexible biosensor patch for continuous and longitudinal monitoring of different physiological signals, including body temperature, blood pressure (BP), and electrocardiography. Moreover, these modalities for tracking body movement and GPS locations for emergency rescue have been included in biosensor devices. We optimized the flexible patch design with high mechanical stretchability and compatibility that can provide reliable and long-term attachment to the curved skin surface. Regarding smart healthcare applications, this research presents an Internet of Things-connected healthcare platform consisting of a smartphone application, website service, database server, and mobile gateway. The IoT platform has the potential to reduce the demand for medical resources and enhance the quality of healthcare services. To further address the advances in non-invasive continuous BP monitoring, an optimized deep learning architecture with one-channel electrocardiogram signals is introduced. The performance of the BP estimation model was verified using an independent dataset; this experimental result satisfied the Association for the Advancement of Medical Instrumentation, and the British Hypertension Society standards for BP monitoring devices. The experimental results demonstrated the practical application of the wireless and flexible biosensor patch for continuous physiological signal monitoring with Internet of Medical Things-connected healthcare applications.https://www.mdpi.com/2079-6374/12/3/139biosensorsphysiological signalsInternet of Medical Things (IoMT)artificial neural network (ANN)
spellingShingle Duc Tri Phan
Cong Hoan Nguyen
Thuy Dung Pham Nguyen
Le Hai Tran
Sumin Park
Jaeyeop Choi
Byeong-il Lee
Junghwan Oh
A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications
Biosensors
biosensors
physiological signals
Internet of Medical Things (IoMT)
artificial neural network (ANN)
title A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications
title_full A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications
title_fullStr A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications
title_full_unstemmed A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications
title_short A Flexible, Wearable, and Wireless Biosensor Patch with Internet of Medical Things Applications
title_sort flexible wearable and wireless biosensor patch with internet of medical things applications
topic biosensors
physiological signals
Internet of Medical Things (IoMT)
artificial neural network (ANN)
url https://www.mdpi.com/2079-6374/12/3/139
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