Ginsenoside Rg1 attenuates LPS-induced chronic renal injury by inhibiting NOX4-NLRP3 signaling in mice

Ginsenoside Rg1 attenuates LPS-induced chronic renal injury by inhibiting NOX4-NLRP3 signaling in mice

Chronic renal injury (CRI) is a common pathological damage in chronic renal disease, and the therapeutic options for preventing its progression are limited at present. Ginsenoside Rg1 (Rg1) is reported to have a protective effect on renal injury by improving oxidative stress and inflammation. Lipopo...

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Bibliographic Details
Main Authors: Duoduo Zhang, Pengmin Ji, Ran Sun, Huimin Zhou, Lei Huang, Liangliang Kong, Weiping Li, Weizu Li
Format: Article
Language:English
Published: Elsevier 2022-06-01
Series:Biomedicine & Pharmacotherapy
Subjects:
Ginsenoside Rg1
Lipopolysaccharide
Chronic renal injury
NLRP3 inflammasome
NADPH oxidase 4
Online Access:http://www.sciencedirect.com/science/article/pii/S0753332222003250

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