Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases

In recent years, there has been a noticeable increase in the incidence of inflammatory bowel diseases in the pediatric population. Entry observations demonstrate anemia, malabsorption, deficiencies in vitamin D and calcium. These aspects, together with the systemic action of pro-inflammatory cytokin...

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Main Authors: Mariusz Olczyk, Elżbieta Czkwianianc, Anna Socha-Banasiak
Format: Article
Language:English
Published: MDPI AG 2022-03-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/12/3/423
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author Mariusz Olczyk
Elżbieta Czkwianianc
Anna Socha-Banasiak
author_facet Mariusz Olczyk
Elżbieta Czkwianianc
Anna Socha-Banasiak
author_sort Mariusz Olczyk
collection DOAJ
description In recent years, there has been a noticeable increase in the incidence of inflammatory bowel diseases in the pediatric population. Entry observations demonstrate anemia, malabsorption, deficiencies in vitamin D and calcium. These aspects, together with the systemic action of pro-inflammatory cytokines and steroid therapy are widely recognized as factors influencing bone metabolism. Presently, however, there are very few studies that can be found in the scientific literature on metabolic disorders in patients with IBD, especially in the pediatric population as the coexistence has not been sufficiently examined and understood. This review aims to summarize the currently available literature, as well as assess which areas have information gaps and need further research.
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spelling doaj.art-72163a2977e24f92bdd2042a0bcc7f472023-11-30T21:14:30ZengMDPI AGLife2075-17292022-03-0112342310.3390/life12030423Metabolic Bone Disorders in Children with Inflammatory Bowel DiseasesMariusz Olczyk0Elżbieta Czkwianianc1Anna Socha-Banasiak2Department of Molecular Pathology and Neuropathology, Medical University of Lodz, Pomorska 251, 92-216 Lodz, PolandDepartment of Gastroenterology, Allergology and Pediatrics, Polish Mother’s Memorial Hospital Research Institute, 93-338 Lodz, PolandDepartment of Gastroenterology, Allergology and Pediatrics, Polish Mother’s Memorial Hospital Research Institute, 93-338 Lodz, PolandIn recent years, there has been a noticeable increase in the incidence of inflammatory bowel diseases in the pediatric population. Entry observations demonstrate anemia, malabsorption, deficiencies in vitamin D and calcium. These aspects, together with the systemic action of pro-inflammatory cytokines and steroid therapy are widely recognized as factors influencing bone metabolism. Presently, however, there are very few studies that can be found in the scientific literature on metabolic disorders in patients with IBD, especially in the pediatric population as the coexistence has not been sufficiently examined and understood. This review aims to summarize the currently available literature, as well as assess which areas have information gaps and need further research.https://www.mdpi.com/2075-1729/12/3/423IBDmetabolic disorderspediatricsbone mineral densityCrohn’s diseaseulcerative colitis
spellingShingle Mariusz Olczyk
Elżbieta Czkwianianc
Anna Socha-Banasiak
Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases
Life
IBD
metabolic disorders
pediatrics
bone mineral density
Crohn’s disease
ulcerative colitis
title Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases
title_full Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases
title_fullStr Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases
title_full_unstemmed Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases
title_short Metabolic Bone Disorders in Children with Inflammatory Bowel Diseases
title_sort metabolic bone disorders in children with inflammatory bowel diseases
topic IBD
metabolic disorders
pediatrics
bone mineral density
Crohn’s disease
ulcerative colitis
url https://www.mdpi.com/2075-1729/12/3/423
work_keys_str_mv AT mariuszolczyk metabolicbonedisordersinchildrenwithinflammatoryboweldiseases
AT elzbietaczkwianianc metabolicbonedisordersinchildrenwithinflammatoryboweldiseases
AT annasochabanasiak metabolicbonedisordersinchildrenwithinflammatoryboweldiseases