Integration analysis identifies the role of metallothionein in the progression from hepatic steatosis to steatohepatitis

BackgroundNon-alcoholic fatty liver disease (NAFLD), a metabolic disorder that develops from non-alcoholic fatty liver (NAFL) to non-alcoholic steatohepatitis (NASH), has become an epidemic of chronic liver dysfunction worldwide. However, mechanisms that govern the transition from NAFL to NASH have...

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Bibliographic Details
Main Authors: Xiaoya Li, Shaoping Zhong, Yifan Sun, Xinmei Huang, Yue Li, Lihong Wang, Yueyue Wu, Min Yang, Hai-Xin Yuan, Jun Liu, Shufei Zang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-10-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2022.951093/full

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