Azide-Alkyne Cycloaddition Catalyzed by a Glucose/Benedict Reagent System

Benedict’s Reagent is commonly used in identifying reducing sugars through a redox process where a Cu(I) species is generated. Despite the simplicity of this reaction, this has barely been investigated as a copper (I) source for catalytic processes. In this report, diverse organic azides and alkynes...

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Bibliographic Details
Main Authors: Jesús G. García Torres, Andrés F. Becerra-Buitrago, Luis Carlos García-Sánchez, Marco A. García-Eleno, M. V. Basavanag Unnamatla, Erick Cuevas-Yañez
Format: Article
Language:English
Published: MDPI AG 2021-11-01
Series:Chemistry Proceedings
Subjects:
Online Access:https://www.mdpi.com/2673-4583/8/1/64
Description
Summary:Benedict’s Reagent is commonly used in identifying reducing sugars through a redox process where a Cu(I) species is generated. Despite the simplicity of this reaction, this has barely been investigated as a copper (I) source for catalytic processes. In this report, diverse organic azides and alkynes were reacted in the presence of catalytic amounts of a Glucose–Benedict Reagent system, obtaining the corresponding 1,2,3-triazoles through a simple and environmentally friendly synthetic procedure.
ISSN:2673-4583