Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications

Background: Early failure of uncemented femoral stems associated with incorrect sizing is a known postoperative complication. Surgeons are often faced with the question of whether an uncemented stem of adequate stability or a larger-sized stem should be implanted, especially when the proximal femora...

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Main Authors: Wang Katherine, Kenanidis Eustathios, Suleman Khurram, Miodownik Mark, Avadi Mahsa, Horne David, Thompson Jonathan, Tsiridis Eleftherios, Moazen Mehran
Format: Article
Language:English
Published: EDP Sciences 2022-01-01
Series:SICOT-J
Subjects:
Online Access:https://www.sicot-j.org/articles/sicotj/full_html/2022/01/sicotj220051/sicotj220051.html
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author Wang Katherine
Kenanidis Eustathios
Suleman Khurram
Miodownik Mark
Avadi Mahsa
Horne David
Thompson Jonathan
Tsiridis Eleftherios
Moazen Mehran
author_facet Wang Katherine
Kenanidis Eustathios
Suleman Khurram
Miodownik Mark
Avadi Mahsa
Horne David
Thompson Jonathan
Tsiridis Eleftherios
Moazen Mehran
author_sort Wang Katherine
collection DOAJ
description Background: Early failure of uncemented femoral stems associated with incorrect sizing is a known postoperative complication. Surgeons are often faced with the question of whether an uncemented stem of adequate stability or a larger-sized stem should be implanted, especially when the proximal femoral cancellous bone is adequate. The biomechanical effect of sub-optimal stem sizing in the femur remains unclear. This study investigated the mechanical behaviour of two sequential sized uncemented stems of the same type. Methods: Six laboratory models of synthetic non-osteoporotic femora were randomly divided into two groups and implanted with either a nominal or oversized uncemented hydroxyapatite-coated nonporous titanium collarless stem. Stiffness, uniaxial strain, and pattern of strain distribution were measured under an anatomical one-legged stance. Results: Oversized stems demonstrated a higher overall stiffness compared to nominal; however, this was not statistically significant. The nominal stem showed a higher strain in the neck and the proximal medial diaphyseal region. The oversized stem showed higher strains in the distal region around the implant tip. Conclusion: Opting to use a larger stem may potentially increase primary stability, thus allowing safer early mobility. However, higher stiffness may lead to stress shielding, bone loss, and thigh pain in the long term. In addition, strains in the diaphysis and the tip of the stem may predispose to periprosthetic fractures, especially in osteoporotic bones, making this a relatable aspect for users and biomechanical loading. Given the wide range of complex factors that need to be considered when choosing stem size in uncemented THA surgery, this study’s results should be interpreted cautiously.
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spelling doaj.art-721c6fbafa0e4d4bb672f4ffc601177a2022-12-22T02:52:16ZengEDP SciencesSICOT-J2426-88872022-01-0184310.1051/sicotj/2022043sicotj220051Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implicationsWang Katherine0https://orcid.org/0000-0002-6900-3213Kenanidis Eustathios1Suleman Khurram2Miodownik Mark3Avadi Mahsa4Horne David5Thompson Jonathan6Tsiridis Eleftherios7Moazen Mehran8Department of Mechanical Engineering, University College LondonDepartment of Mechanical Engineering, University College LondonDepartment of Mechanical Engineering, University College LondonDepartment of Mechanical Engineering, University College LondonDePuy SynthesDePuy SynthesDePuy SynthesDepartment of Mechanical Engineering, University College LondonDepartment of Mechanical Engineering, University College LondonBackground: Early failure of uncemented femoral stems associated with incorrect sizing is a known postoperative complication. Surgeons are often faced with the question of whether an uncemented stem of adequate stability or a larger-sized stem should be implanted, especially when the proximal femoral cancellous bone is adequate. The biomechanical effect of sub-optimal stem sizing in the femur remains unclear. This study investigated the mechanical behaviour of two sequential sized uncemented stems of the same type. Methods: Six laboratory models of synthetic non-osteoporotic femora were randomly divided into two groups and implanted with either a nominal or oversized uncemented hydroxyapatite-coated nonporous titanium collarless stem. Stiffness, uniaxial strain, and pattern of strain distribution were measured under an anatomical one-legged stance. Results: Oversized stems demonstrated a higher overall stiffness compared to nominal; however, this was not statistically significant. The nominal stem showed a higher strain in the neck and the proximal medial diaphyseal region. The oversized stem showed higher strains in the distal region around the implant tip. Conclusion: Opting to use a larger stem may potentially increase primary stability, thus allowing safer early mobility. However, higher stiffness may lead to stress shielding, bone loss, and thigh pain in the long term. In addition, strains in the diaphysis and the tip of the stem may predispose to periprosthetic fractures, especially in osteoporotic bones, making this a relatable aspect for users and biomechanical loading. Given the wide range of complex factors that need to be considered when choosing stem size in uncemented THA surgery, this study’s results should be interpreted cautiously.https://www.sicot-j.org/articles/sicotj/full_html/2022/01/sicotj220051/sicotj220051.htmltotal hip arthroplasty (tha)biomechanicsuncementedexperimentalstiffnessstrainstem size
spellingShingle Wang Katherine
Kenanidis Eustathios
Suleman Khurram
Miodownik Mark
Avadi Mahsa
Horne David
Thompson Jonathan
Tsiridis Eleftherios
Moazen Mehran
Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications
SICOT-J
total hip arthroplasty (tha)
biomechanics
uncemented
experimental
stiffness
strain
stem size
title Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications
title_full Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications
title_fullStr Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications
title_full_unstemmed Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications
title_short Differences between two sequential uncemented stem sizes in total hip arthroplasty: A comparative biomechanical study and potential clinical implications
title_sort differences between two sequential uncemented stem sizes in total hip arthroplasty a comparative biomechanical study and potential clinical implications
topic total hip arthroplasty (tha)
biomechanics
uncemented
experimental
stiffness
strain
stem size
url https://www.sicot-j.org/articles/sicotj/full_html/2022/01/sicotj220051/sicotj220051.html
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