Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome

Carpal tunnel syndrome (CTS) is the most common median nerve compression neuropathy. Its symptoms and clinical presentation are well known. However, symptoms at median nerve distribution can also be caused by a proximal problem. Pronator syndrome (PS) and anterior interosseous nerve syndrome (AINS)...

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Main Authors: Pekka Löppönen, Sina Hulkkonen, Jorma Ryhänen
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Journal of Clinical Medicine
Subjects:
Online Access:https://www.mdpi.com/2077-0383/11/14/3988
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author Pekka Löppönen
Sina Hulkkonen
Jorma Ryhänen
author_facet Pekka Löppönen
Sina Hulkkonen
Jorma Ryhänen
author_sort Pekka Löppönen
collection DOAJ
description Carpal tunnel syndrome (CTS) is the most common median nerve compression neuropathy. Its symptoms and clinical presentation are well known. However, symptoms at median nerve distribution can also be caused by a proximal problem. Pronator syndrome (PS) and anterior interosseous nerve syndrome (AINS) with their typical characteristics have been thought to explain proximal median nerve problems. Still, the literature on proximal median nerve compressions (PMNCs) is conflicting, making this classic split too simple. This review clarifies that PMNCs should be understood as a spectrum of mild to severe nerve lesions along a branching median nerve, thus causing variable symptoms. Clear objective findings are not always present, and therefore, diagnosis should be based on a more thorough understanding of anatomy and clinical testing. Treatment should be planned according to each patient’s individual situation. To emphasize the complexity of causes and symptoms, PMNC should be named proximal median nerve syndrome.
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spelling doaj.art-721f88b0414440fbbdf6c690324e19232023-11-30T21:09:57ZengMDPI AGJournal of Clinical Medicine2077-03832022-07-011114398810.3390/jcm11143988Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel SyndromePekka Löppönen0Sina Hulkkonen1Jorma Ryhänen2Department of Orthopedics and Traumatology, Seinäjoki Central Hospital, FI-60220 Seinäjoki, FinlandDepartment of Hand Surgery, Helsinki University Hospital, University of Helsinki, FI-00029 Helsinki, FinlandDepartment of Hand Surgery, Helsinki University Hospital, University of Helsinki, FI-00029 Helsinki, FinlandCarpal tunnel syndrome (CTS) is the most common median nerve compression neuropathy. Its symptoms and clinical presentation are well known. However, symptoms at median nerve distribution can also be caused by a proximal problem. Pronator syndrome (PS) and anterior interosseous nerve syndrome (AINS) with their typical characteristics have been thought to explain proximal median nerve problems. Still, the literature on proximal median nerve compressions (PMNCs) is conflicting, making this classic split too simple. This review clarifies that PMNCs should be understood as a spectrum of mild to severe nerve lesions along a branching median nerve, thus causing variable symptoms. Clear objective findings are not always present, and therefore, diagnosis should be based on a more thorough understanding of anatomy and clinical testing. Treatment should be planned according to each patient’s individual situation. To emphasize the complexity of causes and symptoms, PMNC should be named proximal median nerve syndrome.https://www.mdpi.com/2077-0383/11/14/3988carpal tunnel syndromemedian neuropathymedian nerve entrapmentneuralgic amyotrophypronator syndrome
spellingShingle Pekka Löppönen
Sina Hulkkonen
Jorma Ryhänen
Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome
Journal of Clinical Medicine
carpal tunnel syndrome
median neuropathy
median nerve entrapment
neuralgic amyotrophy
pronator syndrome
title Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome
title_full Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome
title_fullStr Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome
title_full_unstemmed Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome
title_short Proximal Median Nerve Compression in the Differential Diagnosis of Carpal Tunnel Syndrome
title_sort proximal median nerve compression in the differential diagnosis of carpal tunnel syndrome
topic carpal tunnel syndrome
median neuropathy
median nerve entrapment
neuralgic amyotrophy
pronator syndrome
url https://www.mdpi.com/2077-0383/11/14/3988
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