Antenatally diagnosed alobar holoprosencephaly: A report of two cases
Holoprosencephaly is a complex developmental abnormality of the brain arising from the failure of cleavage of the prosencephalon. The condition termed “holoprosencephaly” includes cyclopia, cebocephaly, ethmocephaly, and median cleft. We present two cases of antenatally diagnosed alobar holoprosence...
Main Authors: | , , , |
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Format: | Article |
Language: | English |
Published: |
Wolters Kluwer Medknow Publications
2017-01-01
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Series: | CHRISMED Journal of Health and Research |
Subjects: | |
Online Access: | http://www.cjhr.org/article.asp?issn=2348-3334;year=2017;volume=4;issue=4;spage=283;epage=285;aulast=Srinivasa |
Summary: | Holoprosencephaly is a complex developmental abnormality of the brain arising from the failure of cleavage of the prosencephalon. The condition termed “holoprosencephaly” includes cyclopia, cebocephaly, ethmocephaly, and median cleft. We present two cases of antenatally diagnosed alobar holoprosencephaly with multiple associations, which were confirmed after termination of pregnancy. One of them had a proboscis and a single midline eye. The other had multiple facial abnormalities such as hypotelorism, median cleft lip and palate, and preauricular skin tag. |
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ISSN: | 2348-3334 2348-506X |