Antifungal Activity of <i>Angelica gigas</i> with Enhanced Water Solubility of Decursin and Decursinol Angelate by Hot-Melt Extrusion Technology against <i>Candida albicans</i>

Antifungal Activity of <i>Angelica gigas</i> with Enhanced Water Solubility of Decursin and Decursinol Angelate by Hot-Melt Extrusion Technology against <i>Candida albicans</i>

Hot-melt extrusion (HME) has been an alternative technique to improve the solubility and bioavailability of active molecules with low water solubility. In this study, HME-<i>Angelica gigas</i> Nakai (AGN) was prepared to increase the aqueous solubility of decursin (D) and decursinol ange...

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Bibliographic Details
Main Authors: Suji Ryu, Ha Yeon Lee, Seoul-Hee Nam, Jong-Suep Baek
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:International Journal of Translational Medicine
Subjects:
<i>Angelica gigas</i>
hot-melt extrusion
antifungal activity
<i>Candida albicans</i>
Online Access:https://www.mdpi.com/2673-8937/2/4/38

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