Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies
In the last decades understanding the relationship between the circulating platelets and the biological aggressivity of ovarian cancer gave the opportunity to researchers to introduce new therapeutic lines in ovarian cancer patients with promising results. Therefore, this subject has become intensiv...
| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Amaltea Medical Publishing House
2022-09-01
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| Series: | Romanian Medical Journal |
| Subjects: | |
| Online Access: | https://rmj.com.ro/articles/2022.3/RMJ_2022_3_Art-08.pdf |
| _version_ | 1827361474193915904 |
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| author | Irina Balescu Nicoale Bacalbasa Iulian Brezean Claudia Stoica Cezar Laurentiu Tomescu Cristina Martac Andrei Voichitoiu Bogdan Gaspar |
| author_facet | Irina Balescu Nicoale Bacalbasa Iulian Brezean Claudia Stoica Cezar Laurentiu Tomescu Cristina Martac Andrei Voichitoiu Bogdan Gaspar |
| author_sort | Irina Balescu |
| collection | DOAJ |
| description | In the last decades understanding the relationship between the circulating platelets and the biological aggressivity of ovarian cancer gave the opportunity to researchers to introduce new therapeutic lines in ovarian cancer patients with promising results. Therefore, this subject has become intensively studied and surprising correlation ships have been observed. One of the most recently investigated issues regards the influence of circulating platelets on epithelial ovarian cancer refers to the platelets’ ability to induce the epithelial to mesenchymal transition. The current paper aims to discuss about this subject and about the clinical implications of the process. |
| first_indexed | 2024-03-08T07:05:47Z |
| format | Article |
| id | doaj.art-7227f1aa951f4db59abda535e8e8c32b |
| institution | Directory Open Access Journal |
| issn | 1220-5478 2069-606X |
| language | English |
| last_indexed | 2024-03-08T07:05:47Z |
| publishDate | 2022-09-01 |
| publisher | Amaltea Medical Publishing House |
| record_format | Article |
| series | Romanian Medical Journal |
| spelling | doaj.art-7227f1aa951f4db59abda535e8e8c32b2024-02-03T04:52:35ZengAmaltea Medical Publishing HouseRomanian Medical Journal1220-54782069-606X2022-09-0169311311510.37897/RMJ.2022.3.8Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapiesIrina Balescu0Nicoale Bacalbasa1Iulian Brezean2Claudia Stoica3Cezar Laurentiu Tomescu4Cristina Martac5 Andrei Voichitoiu6Bogdan Gaspar7Doctoral School, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Surgery, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, RomaniaDepartment of Surgery, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Surgery , ”Ion Cantacuzino” Clinical Hospital, Bucharest, RomaniaDepartment of Anatomy, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Surgery, ”Ilfov” County Emergency Hospital, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, County Hospital Constanta, Romania; ”Ovidius” University of Medicine and Pharmacy, Constanta, RomaniaDepartment of Anesthesiology, Fundeni Clinical Institute, Bucharest, RomaniaDepartment of Obstetrics and Gynecology, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Obstetrics and Gynecology National Institute of Mother and Child Care Alessandrescu-Rusescu, Bucharest, RomaniaDepartment of Surgery, ”Carol Davila” University of Medicine and Pharmacy, Bucharest, Romania; Department of Visceral Surgery, ”Floreasca” Clinical Emergency Hospital, Bucharest, RomaniaIn the last decades understanding the relationship between the circulating platelets and the biological aggressivity of ovarian cancer gave the opportunity to researchers to introduce new therapeutic lines in ovarian cancer patients with promising results. Therefore, this subject has become intensively studied and surprising correlation ships have been observed. One of the most recently investigated issues regards the influence of circulating platelets on epithelial ovarian cancer refers to the platelets’ ability to induce the epithelial to mesenchymal transition. The current paper aims to discuss about this subject and about the clinical implications of the process.https://rmj.com.ro/articles/2022.3/RMJ_2022_3_Art-08.pdfepithelial to mesenchymal transitionovarian cancerplatelets |
| spellingShingle | Irina Balescu Nicoale Bacalbasa Iulian Brezean Claudia Stoica Cezar Laurentiu Tomescu Cristina Martac Andrei Voichitoiu Bogdan Gaspar Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies Romanian Medical Journal epithelial to mesenchymal transition ovarian cancer platelets |
| title | Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies |
| title_full | Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies |
| title_fullStr | Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies |
| title_full_unstemmed | Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies |
| title_short | Understanding the relationship between circulating platelets and epithelial to mesenchymal transition – a step towards in discovering new epithelial ovarian cancer targeted therapies |
| title_sort | understanding the relationship between circulating platelets and epithelial to mesenchymal transition a step towards in discovering new epithelial ovarian cancer targeted therapies |
| topic | epithelial to mesenchymal transition ovarian cancer platelets |
| url | https://rmj.com.ro/articles/2022.3/RMJ_2022_3_Art-08.pdf |
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