The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria
Since recent global pandemic started, there has been a high demand for establishing an inexpensive but effective method to interfere with the spread of infectious diseases. Here, we have tested several combinations of violet light (V, 405 nm) with infra-red (IR, 850 nm) to identify an optimal light...
| Main Authors: | , , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2023-04-01
|
| Series: | Journal of Photochemistry and Photobiology |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2666469023000088 |
| _version_ | 1797867598835089408 |
|---|---|
| author | Areli Martinez Karina Hernandez-Quijada Anurupa A. Ghosh Gabriela Cabrera Derrick Scott Anthea Aikins Dinesh K. Verma Igsoo Kwon Yong-Hwan Kim |
| author_facet | Areli Martinez Karina Hernandez-Quijada Anurupa A. Ghosh Gabriela Cabrera Derrick Scott Anthea Aikins Dinesh K. Verma Igsoo Kwon Yong-Hwan Kim |
| author_sort | Areli Martinez |
| collection | DOAJ |
| description | Since recent global pandemic started, there has been a high demand for establishing an inexpensive but effective method to interfere with the spread of infectious diseases. Here, we have tested several combinations of violet light (V, 405 nm) with infra-red (IR, 850 nm) to identify an optimal light for suppressing pathogens. Our results demonstrate that both violet only (4 V) and 3V-1IR (3:1 ratio in combination of violet and infra-red) effectively suppressed all the bacterial growth tested, including Gram-negative and -positive multi-drug resistant (MDR) strains. Both 4 V and 3V-1IR equally terminated standard strains of Escherichia coli and Staphylococcus aureus, as well as MDR-strains (E. coli, Salmonella enterica and S. aureus from ATCC) effectively. In mechanism, the violet light enhanced the level of reactive oxygen species (ROS) for bactericidal effects, however, we have observed a slightly higher potency from 3V-1IR at a shorter distance, probably due to mild heat-derived dehydration by IR. Therefore, we suggest to expose 3V-1IR for short distance applications (≤1 meter) and both 4 V and 3V-1IR for longer distance (≥1 m). Notably, our results strongly suggest that the exposure of safe violet light or with infra-red can be an effective method to suppress the potential spread of bacteria-derived infectious diseases. |
| first_indexed | 2024-04-09T23:42:45Z |
| format | Article |
| id | doaj.art-72287308b17e4c6491649d859ae12ce1 |
| institution | Directory Open Access Journal |
| issn | 2666-4690 |
| language | English |
| last_indexed | 2024-04-09T23:42:45Z |
| publishDate | 2023-04-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Journal of Photochemistry and Photobiology |
| spelling | doaj.art-72287308b17e4c6491649d859ae12ce12023-03-18T04:42:53ZengElsevierJournal of Photochemistry and Photobiology2666-46902023-04-0114100167The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteriaAreli Martinez0Karina Hernandez-Quijada1Anurupa A. Ghosh2Gabriela Cabrera3Derrick Scott4Anthea Aikins5Dinesh K. Verma6Igsoo Kwon7Yong-Hwan Kim8Department of Biological Sciences, Delaware State University, Dover, DE 19901, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USAAnalog Chip Productions (ACP) Technology Inc., 2880 Zanker Road, San Jose, CA 95134, USADepartment of Biological Sciences, Delaware State University, Dover, DE 19901, USA; Corresponding author.Since recent global pandemic started, there has been a high demand for establishing an inexpensive but effective method to interfere with the spread of infectious diseases. Here, we have tested several combinations of violet light (V, 405 nm) with infra-red (IR, 850 nm) to identify an optimal light for suppressing pathogens. Our results demonstrate that both violet only (4 V) and 3V-1IR (3:1 ratio in combination of violet and infra-red) effectively suppressed all the bacterial growth tested, including Gram-negative and -positive multi-drug resistant (MDR) strains. Both 4 V and 3V-1IR equally terminated standard strains of Escherichia coli and Staphylococcus aureus, as well as MDR-strains (E. coli, Salmonella enterica and S. aureus from ATCC) effectively. In mechanism, the violet light enhanced the level of reactive oxygen species (ROS) for bactericidal effects, however, we have observed a slightly higher potency from 3V-1IR at a shorter distance, probably due to mild heat-derived dehydration by IR. Therefore, we suggest to expose 3V-1IR for short distance applications (≤1 meter) and both 4 V and 3V-1IR for longer distance (≥1 m). Notably, our results strongly suggest that the exposure of safe violet light or with infra-red can be an effective method to suppress the potential spread of bacteria-derived infectious diseases.http://www.sciencedirect.com/science/article/pii/S2666469023000088405 nm850 nmMDR bacteria suppressionCombined lightsROS generation |
| spellingShingle | Areli Martinez Karina Hernandez-Quijada Anurupa A. Ghosh Gabriela Cabrera Derrick Scott Anthea Aikins Dinesh K. Verma Igsoo Kwon Yong-Hwan Kim The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria Journal of Photochemistry and Photobiology 405 nm 850 nm MDR bacteria suppression Combined lights ROS generation |
| title | The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria |
| title_full | The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria |
| title_fullStr | The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria |
| title_full_unstemmed | The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria |
| title_short | The combination of violet light and infra-red as well as violet light only effectively suppress the survival of multiple-drug resistant bacteria |
| title_sort | combination of violet light and infra red as well as violet light only effectively suppress the survival of multiple drug resistant bacteria |
| topic | 405 nm 850 nm MDR bacteria suppression Combined lights ROS generation |
| url | http://www.sciencedirect.com/science/article/pii/S2666469023000088 |
| work_keys_str_mv | AT arelimartinez thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT karinahernandezquijada thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT anurupaaghosh thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT gabrielacabrera thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT derrickscott thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT antheaaikins thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT dineshkverma thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT igsookwon thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT yonghwankim thecombinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT arelimartinez combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT karinahernandezquijada combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT anurupaaghosh combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT gabrielacabrera combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT derrickscott combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT antheaaikins combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT dineshkverma combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT igsookwon combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria AT yonghwankim combinationofvioletlightandinfraredaswellasvioletlightonlyeffectivelysuppressthesurvivalofmultipledrugresistantbacteria |