Reward and Immune Systems in Emotion (RISE) prospective longitudinal study: Protocol overview of an integrative reward-inflammation model of first onset of major depression in adolescence

Reward and Immune Systems in Emotion (RISE) prospective longitudinal study: Protocol overview of an integrative reward-inflammation model of first onset of major depression in adolescence

Background: Depression is associated with a reduced sensitivity to rewards and low reward-related brain function in cortico-striatal circuitry. A separate literature documents elevated peripheral inflammation in depression. Recently, integrated reward-inflammation models of depression have been prop...

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Bibliographic Details
Main Authors: Lauren B. Alloy, Iris K.-Y. Chat, Mora M. Grehl, Auburn R. Stephenson, Zoe V. Adogli, Thomas M. Olino, Lauren M. Ellman, Gregory E. Miller, Robin Nusslock
Format: Article
Language:English
Published: Elsevier 2023-07-01
Series:Brain, Behavior, & Immunity - Health
Subjects:
Depression
Inflammation
Reward responsiveness
fMRI
Stress
Adversity
Online Access:http://www.sciencedirect.com/science/article/pii/S2666354623000571

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