Divergent Effects of Systemic and Intracollicular CB Receptor Activation Against Forebrain and Hindbrain-Evoked Seizures in Rats
Cannabinoid (CB) receptor agonists are of growing interest as targets for anti-seizure therapies. Here we examined the effect of systemic administration of the CB receptor agonist WIN 55,212-2 (WIN) against audiogenic seizures (AGSs) in the Genetically Epilepsy Prone Rat (GEPR)-3 strain, and against...
Main Authors: | Victor R. Santos, Robert Hammack, Evan Wicker, Prosper N’Gouemo, Patrick A. Forcelli |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2020-11-01
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Series: | Frontiers in Behavioral Neuroscience |
Subjects: | |
Online Access: | https://www.frontiersin.org/articles/10.3389/fnbeh.2020.595315/full |
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