Electrophysiological and structural determinants of electrotonic modulation of repolarization by the activation sequence

Spatial dispersion of repolarization is known to play an important role in arrhythmogenesis. Electrotonic modulation of repolarization by the activation sequence has been observed in some species and tissue preparations, but to varying extents. Our study sought to determine the mechanisms underlying...

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Bibliographic Details
Main Authors: Richard David Walton, Alan eBenson, Matthew eHardy, Ed eWhite, Olivier eBernus
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-10-01
Series:Frontiers in Physiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2013.00281/full