Nalfurafine Hydrochloride, a κ-Opioid Receptor Agonist, Induces Melanophagy via PKA Inhibition in B16F1 Cells

Nalfurafine Hydrochloride, a κ-Opioid Receptor Agonist, Induces Melanophagy via PKA Inhibition in B16F1 Cells

Selective autophagy controls cellular homeostasis by degrading unnecessary or damaged cellular components. Melanosomes are specialized organelles that regulate the biogenesis, storage, and transport of melanin in melanocytes. However, the mechanisms underlying melanosomal autophagy, known as the mel...

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Bibliographic Details
Main Authors: Ha Jung Lee, Seong Hyun Kim, Yong Hwan Kim, So Hyun Kim, Gyeong Seok Oh, Ji-Eun Bae, Joon Bum Kim, Na Yeon Park, Kyuhee Park, Eunbyul Yeom, Kwiwan Jeong, Pansoo Kim, Doo Sin Jo, Dong-Hyung Cho
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cells
Subjects:
nalfurafine hydrochloride
autophagy
κ-opioid receptor
melanophagy
B16F1 cells
Online Access:https://www.mdpi.com/2073-4409/12/1/146

Internet

https://www.mdpi.com/2073-4409/12/1/146

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