Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data)
Aim. To assess the prevalence of non-alcoholic fatty liver disease (NAFLD) using the liver obesity index — FLI (Fatty Liver Index), and to study its associations with socio-demographic indicators and behavioral risk factors for NAFLD.Material and methods. The data from the multicenter ESSE-RF study...
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«SILICEA-POLIGRAF» LLC
2022-10-01
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| Series: | Кардиоваскулярная терапия и профилактика |
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| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/3356 |
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| author | S. E. Evstifeeva S. A. Shalnova V. A. Kutsenko E. V. Yarovaya Yu. A. Balanova A. E. Imaeva A. V. Kapustina G. A. Muromtseva S. A. Maksimov N. S. Karamnova A. G. Soplenkova E. M. Filichkina I. A. Viktorova N. N. Prishchepa A. N. Redko S. S. Yakushin O. M Drapkina |
| author_facet | S. E. Evstifeeva S. A. Shalnova V. A. Kutsenko E. V. Yarovaya Yu. A. Balanova A. E. Imaeva A. V. Kapustina G. A. Muromtseva S. A. Maksimov N. S. Karamnova A. G. Soplenkova E. M. Filichkina I. A. Viktorova N. N. Prishchepa A. N. Redko S. S. Yakushin O. M Drapkina |
| author_sort | S. E. Evstifeeva |
| collection | DOAJ |
| description | Aim. To assess the prevalence of non-alcoholic fatty liver disease (NAFLD) using the liver obesity index — FLI (Fatty Liver Index), and to study its associations with socio-demographic indicators and behavioral risk factors for NAFLD.Material and methods. The data from the multicenter ESSE-RF study (Epidemiology of cardiovascular diseases in the regions of the Russian Federation) — samples from the unorganized male and female population aged 25-64 years were used. 5,161 respondents were included, of which 2,275 (44,1%) were men. To assess the prevalence of NAFLD, the liver obesity index FLI was used, calculated according to the formula by Bedogni G, et al. (2006). A high FLI index ≥60 was considered a predictor of liver steatosis.Results. High FLI ≥60 was detected in 38,5% of men and 26,6% of women. Multivariate analysis of associations of high FLI index in men and women showed a strong relationship with age: men — odds ratio (OR) 5,01, 95% confidence interval (CI): 3,82-6,59 (p<0,0001) and women — OR 8,58, 95% CI: 6,39-11,64 (p<0,0001), living in rural areas: men — OR 1,32, 95% CI: 1,06-1,63 (p=0,011) and women — OR 1,4, 95% CI: 1,15-1,71 (p=0,001). The FLI index ≥60 was significantly associated with low physical activity (p=0,001) in men and current smoking in women (p=0,013).Conclusion. A high FLI index ≥60 is most common among men, significantly associated with age, living in rural areas, currently smoking women, and low physical activity men. Higher education, in relation to FLI ≥60, had a protective effect on women. |
| first_indexed | 2024-04-10T03:33:04Z |
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| id | doaj.art-723046df36dc474aa790fafa61fa0c98 |
| institution | Directory Open Access Journal |
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| language | Russian |
| last_indexed | 2024-04-10T03:33:04Z |
| publishDate | 2022-10-01 |
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| series | Кардиоваскулярная терапия и профилактика |
| spelling | doaj.art-723046df36dc474aa790fafa61fa0c982023-03-13T07:23:33Zrus«SILICEA-POLIGRAF» LLCКардиоваскулярная терапия и профилактика1728-88002619-01252022-10-0121910.15829/1728-8800-2022-33562537Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data)S. E. Evstifeeva0S. A. Shalnova1V. A. Kutsenko2E. V. Yarovaya3Yu. A. Balanova4A. E. Imaeva5A. V. Kapustina6G. A. Muromtseva7S. A. Maksimov8N. S. Karamnova9A. G. Soplenkova10E. M. Filichkina11I. A. Viktorova12N. N. Prishchepa13A. N. Redko14S. S. Yakushin15O. M Drapkina16ФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава России; ФГБОУ ВО «Московский государственный университет имени М.В. Ломоносова»ФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава России; ФГБОУ ВО «Московский государственный университет имени М.В. Ломоносова»ФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииФГБОУ ВО "Омский государственный медицинский университет" Минздрава РоссииГБУЗ Республики Карелия "Городская поликлиника № 1"ФГБОУ ВО "Кубанский государственный медицинский университет" Минздрава РоссииФГБОУ ВО "Рязанский государственный медицинский университет им. акад. И. П. Павлова" Минздрава РоссииФГБУ "Национальный медицинский исследовательский центр терапии и профилактической медицины" Минздрава РоссииAim. To assess the prevalence of non-alcoholic fatty liver disease (NAFLD) using the liver obesity index — FLI (Fatty Liver Index), and to study its associations with socio-demographic indicators and behavioral risk factors for NAFLD.Material and methods. The data from the multicenter ESSE-RF study (Epidemiology of cardiovascular diseases in the regions of the Russian Federation) — samples from the unorganized male and female population aged 25-64 years were used. 5,161 respondents were included, of which 2,275 (44,1%) were men. To assess the prevalence of NAFLD, the liver obesity index FLI was used, calculated according to the formula by Bedogni G, et al. (2006). A high FLI index ≥60 was considered a predictor of liver steatosis.Results. High FLI ≥60 was detected in 38,5% of men and 26,6% of women. Multivariate analysis of associations of high FLI index in men and women showed a strong relationship with age: men — odds ratio (OR) 5,01, 95% confidence interval (CI): 3,82-6,59 (p<0,0001) and women — OR 8,58, 95% CI: 6,39-11,64 (p<0,0001), living in rural areas: men — OR 1,32, 95% CI: 1,06-1,63 (p=0,011) and women — OR 1,4, 95% CI: 1,15-1,71 (p=0,001). The FLI index ≥60 was significantly associated with low physical activity (p=0,001) in men and current smoking in women (p=0,013).Conclusion. A high FLI index ≥60 is most common among men, significantly associated with age, living in rural areas, currently smoking women, and low physical activity men. Higher education, in relation to FLI ≥60, had a protective effect on women.https://cardiovascular.elpub.ru/jour/article/view/3356неалкогольная жировая болезнь печенираспространенностьfatty liver index. |
| spellingShingle | S. E. Evstifeeva S. A. Shalnova V. A. Kutsenko E. V. Yarovaya Yu. A. Balanova A. E. Imaeva A. V. Kapustina G. A. Muromtseva S. A. Maksimov N. S. Karamnova A. G. Soplenkova E. M. Filichkina I. A. Viktorova N. N. Prishchepa A. N. Redko S. S. Yakushin O. M Drapkina Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data) Кардиоваскулярная терапия и профилактика неалкогольная жировая болезнь печени распространенность fatty liver index. |
| title | Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data) |
| title_full | Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data) |
| title_fullStr | Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data) |
| title_full_unstemmed | Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data) |
| title_short | Prevalence of non-alcoholic fatty liver disease among the working-age population: associations with socio-demographic indicators and behavioral risk factors (ESSE RF-2 data) |
| title_sort | prevalence of non alcoholic fatty liver disease among the working age population associations with socio demographic indicators and behavioral risk factors esse rf 2 data |
| topic | неалкогольная жировая болезнь печени распространенность fatty liver index. |
| url | https://cardiovascular.elpub.ru/jour/article/view/3356 |
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